Our CompanyQuanta BioDesign, Ltd., is located in Powell, Ohio, a suburb of Columbus, the home of The Ohio State University. Founded in 1997 by Paul D. Davis, Ph.D. under the name BioOrganic Technologies, LLC, he moved into our original and current location in March of 1998. In Spring of 1999, we changed our name to Quanta BioDesign, Ltd., in order to better reflect our company mission. Quanta BioDesign was founded for the purpose of developing and commercializing an extensive line of products for companies involved in drug discovery and diagnostic development programs. These products are based on our proprietary discrete polyethylene glycol (dPEG®) chemistries, including our unique processes for making these important compounds. Our single molecular weight ethylene glycol conjugation technology, dPEG®, can eliminate common problems found in the development of diagnostic and therapeutic products, such as aggregation and non-specific interactions, poor water solubility, poor delivery, delivery issues/options, short serum half life, toxicity and antigenicity. The dPEG® product line is a unique technology platform which can be custom tailored to meet specific physical, chemical and morphological requirements in a broad array of diagnostic and therapeutic applications. Chemistry applications which incorporate dPEG® products include conjugations, simple chemical modifications, cross linking, biotinylation, signal amplification, modification of biological therapeutics and peptide synthesis. Recently we introduced dPEG®; products that offer new delivery options as well. We are involved in developing new cross-linking and labeling chemistries that incorporate the dPEG® technology, and will allow for completely new approaches to existing opportunities in these same areas of therapeutic and diagnostic development, and will revolutionize many of these areas as the new generations of drugs and diagnostics evolve. Paul’s StoryPaul came back to Ohio in 1997 to live where his late wife, Susan, grew up. He decided to pursue his visions for affecting the therapeutic and diagnostic fields of medicine using his passion and creativity in designing chemistry for these markets. Paul’s initial vision is to fully develop the potential and power of a broad range of specifically designed monodispersed (dPEG®) reagents for application in these markets. His previous experiences in both the R&D and manufacturing sides of the business at Molecular Probes, Pierce Biotechnology, and Mead Corp., gives him a very practical and broad background for this vision, as well as sound experience for running the business. Paul’s late wife, Susan, a non-smoker, died in the spring of 1999 from lung cancer (primary) and bone cancer (metastatic). Her death occasioned a deeper passion and commitment on Paul’s part to work closely with both diagnostic (early detection) and therapeutic (control and cure) companies to find better and new solutions to the challenges that are faced in confronting all kinds of disease states. His vision includes a very active involvement in creating new approaches to detection technologies, as well as some interesting and unusual thoughts in the therapeutic arena as well. For now, some of that will have to be played out through our tremendously creative, passionate, and skilled customers. Also, if you like love stories, you have to ask Paul about his journey to marrying Wren (our Business Manager). Our PeopleAs a small company, Quanta BioDesign, Ltd., has the advantage of great flexibility that is created by being “lean and mean.” Everyone has their hands in our process tree of producing our current product offerings. We currently have four Chemists, two Lab Techs and four Office Staff. Paul Davis, Ph.D. - Even though Paul is busy with the everyday work of running a company, you can still find him in the lab a lot of the time, always working to develop new products for our customers. Paul received his Ph.D. in Chemistry from Bowling Green State University. He received his Bachelor of Science in Chemistry and Physics at Point Loma Nazarene University. J.K. "Sandy" Mueller, Jr. - Received a Bachelor of Science in Engineering majoring in Chemical Engineering from Case Institute of Technology in 1970 and a Juris Doctor Degree from the College of Law at The Ohio State University in 1973. He was an Adjunct Professor of Law at Capital University Law School (1985-1999) where he taught courses in Intellectual Property Law and Patent Law. Mr. Mueller is registered to practice before the United States Patent and Trademark Office. Mr. Mueller serves Quanta as its general counsel where he overseas all of Quanta’s legal needs, including patents and trademarks. Alex Pokora, M.S. - Alex is responsible for developing a strategy, in conjunction with the management team and the R & D group, for monitoring and growing both the short term sales and long term sales to maximize the potential of the business. He has had extensive experience with Marketing, Management and Research in the chemistry field. He received his B.S. from Rutgers and his M.S. in Chemistry from The Ohio State University. Robert Woodman, Ph.D. – As Sr. Product Development Scientist, Robert’s skills as an organic chemist, having a strong biology flavor, gives us a more balanced and broader perspective on our work. He develops new products and works on manufacture of established products. He received his Bachelor of Science in Microbiology from University of Southern Mississippi. Robert received his Ph.D. in Biochemistry from The Ohio State University. Richard Brody, Ph.D. - Rich is protein biochemist who is part of our applications group. He has extensive experience in the modification and characterization of proteins as well as in assay development. Currently, Rich is developing new uses for our dPEG® products for both diagnostic and therapeutic applications. He received his B.A. from Cornell and his Ph.D. from Harvard. Arfaan Rampersaud, Ph. D. - Arfaan is a biochemist with special interests in the use of dPEGs to develop new products in the field of nanomaterials. He also works in the applications group developing antibody conjugates and enzyme conjugates using dPEG technology. Arfaan recieved his BS in Chemistry from Defiance College and PhD in Biochemistry from Kent State University. James Guyo, M.S. and MBA - James is a Sr. Process Development Scientist and involved in process development and optimization, research and development and scale-up activities among other things. He also has extensive experience doing contract cGMP. He received his BS in Chemistry and Biochemistry from the University of Zimbabwe in 1996 and graduated with an MBA in 2002 and a Masters in Chemistry in 2004 from Wright State University. Dennis Conn – Dennis is a Sr. Product Development Scientist at QBD. He has been employed in chemical laboratories since 1982 and then in large scale production and special synthesis and marketing with Pierce Chemical. Paul was his supervisor at Pierce and has been his mentor in organic chemistry. In 2003, Dennis joined Paul again at QBD. Dennis has also filled R&D positions in the United States as well as in Israel. He has his BS in chemistry from Eastern Illinois University, Charleston, Illinois. Matt Giese, M.S. and M.S. – As a Sr. Product Development Scientist, Matt is involved in the development of new products, the synthesis of established products, and scale-up activities. He received his BS in Chemistry from the University of Wisconsin–Parkside in 1998, an M.S. in chemistry with a concentration in physical chemistry from Florida State University in 2000, and an M.S. in chemistry with a concentration in organic chemistry from Indiana University-Purdue University at Indianapolis in 2004. After a short time in diagnostics and a successful career in the pharmaceutical industry, Matt came to join the team at QBD. Dan Dawson, M.S. - Dan is a process development chemist involved in process development and scale-up activities. He received his BS in Chemistry from the University of Indianapolis in 2006, and his M.S. in Organic Chemistry from the University of Michigan in 2008. Adam Fulkert - is a separation chemist involved in chromatographing reactions and developing methods for scale up. He received his B.S. in Chemistry from The Ohio State University in fall of 2011. Scott Rogers - is a process development chemist currently working on production of intermediates. He received his BA in Chemistry from Colgate University in 2011. Bryan Davis – Bryan is our Process Development Chemist and currently involved in the process development and scale up activities as well as general maintenance of lab equipment. He is in his second year of college and currently enrolled at Columbus State Community College. Bryan is pursuing a degree in Chemistry. Lab Techs:Katie Davis // Sam Yousef // Tyler Brewer // Yassir Sheikhaldeen // Melissa Vermillion Office Staff:Wren Davis - Business Manager // Stephanie Hampton - Human Resources // Alison Durso - Office Manager // Selena Cantley - Business Development Assistant // Tanja Schneider - Office Assistant // Jeff Sedlock - Systems Administrator |


