Diagnostics

An Effective Targeted Nanoglobular Manganese(II) Chelate Conjugate for Magnetic Resonance Molecular Imaging of Tumor Extracellular Matrix, Mingqian Tan, Xueming Wu, Eun-Kee Jeong, Qianjin Chen, Dennis L. Parker, and Zheng-Rong Lu, Molecular Pharmaceutics, on line-May 19, 2010. DOI: 10.1021/mp100054m. See Products 10503, 10511.

Design and Synthesis of Bis-Biotin-Containing Reagents for Applications Utilizing Monoclonal Antibody-Based Pretargeting system with Streptavidin Mutants, D. Scott Wibur, Steven I. Park, Ming-Kuan Chyan, Feng Wan, Donald K. Hamlin, Jaideep Shenoi, Yukang Lin, Shani M. Wilbur, Franz Buchegger, Anastasia Pantelias, John M. Pagel, and Oliver W. Press, Bioconjugate Chem. 2010, 21, 1225-1238. DOI: 10.1021/bc100030q. See Product 10225.

A Modular Platform for the Rapid Site-Specific Radiolabeling of Proteins with F Exemplified by Quantitative Positron Emission Tomography of Human Epidermal Growth Factor Receptor 2, Herman S. Gill, Jeff N. Tinianow, Annie Pgasawara, Judith E. Flores, Alexander N. Vanderbilt, Helga Raab, Justin M. Scheer, Richard Vandlen, Simon-P. Williams, and Jan Marik, J. Med. Chem. 2009, 52, 5816-5825. DOI: 10.1021/jm900420c. See Product 10503.

Antigen Peptide-Based Immunosensors for Rapid Detection of Antibodies and Antigens, Ling Tian and Tomasz Heyduk, Anal. Chem., 2009, 81 (13), pp 5218-5225. DOI: 10.1021/ac900845a. See Product 10314.

Development of a sensitive surface Plasmon resonance immunosensor for detection of 2, 4-dinitrotoluene with a novel oligo (ethylene glycol)-based sensor surface, Kazutaka Nagatomo, Toshikazu Kawaguchi, Norio Miura, Kiyoshi Toko, Kiyoshi Matsumoto, Talanta 79 (2009) 1142-1148. DOI:10.1016/j.talanta.2009.02.018. See Product 10287.

New Enzyme-Activated Solubility-Switchable Contrast Agent for Magnetic Resonance Imaging: From Synthesis to in Vivo Imaging, Beata Jastrzabska, Rejean Lebel, Helene Therriault, J. Oliver McIntyre, Emanuel Escher, Briggitte Guerin, Benoit Paquette, Witold A. Neugebauer, and Martin Lepage, J. Med. Chem. 2009, 52, 1576-1581. DOI: 10.1021/jm801411h. See Product 10273.

Novel Synthetic Route to Peptide-Capped Gold Nanoparticles, Takeshi Serizawa, Yu Hirai, and Mamoru Aizawa, Langmuir 2009, 25(20, 12229-12234. DOI: 10.1021/la9021799. See Product 10213.

On-Bead Screening of Combinatorial Libraries: Reduction of Nonspecific Binding by Decreasing Surface Ligand Density, Xianwen Chen, Pauline H. Tan, Yanyan Zhang and Dehua Pei, J. Comb. Chem., 2009, 11 (4), pp 604-611. See Product 10200.

Development of an oligo (ethylene glycol)-based SPR immunosensor for TNT detection, Yutaka Mizuta, Takeshi Onodera, Praveen Singh, Kiyoshi Matsumoto, Norio Miura, Kiyoshi Toko, Biosensors and Bioelectronics 24 (2008) 191-197. DOI:10.1016/j.bios.2008.03.042. See Products 10172, 10249.

Functional PEG-Modified Thin Films for Biological Detection, Aaron S. Anderson, Andrew M. Dattelbaum, Gabriel A. Montano, Dominique N. Price, Jurgen G. Schmidt, Jennifer S. Martinez, W. Kevin Grace, Karen M. Grace, and Basil I. Swanson, Langmuir 2008, 24, 2240-2247. DOI: 10.1021/la7033438. See Products 10234, 10243.

Genotyping by allele-specific L-DNA-tagged PCR, Gosuke Hayashi, Masaki Hagihara, Kazuhiko Nakatani, Journal of Biotechnology 135 (2008) 157-160. DOI: 10.1016/j.jbiotec.2008.03.011. See Product 10284.

Molecular Pincers: Antibody-Based Homogeneous Protein Sensors, Ewa Heyduk, Benjamin Dummit, yie-Hwa Chang, and Tomasz Heyduk, Anal. Chem. 2008, 80, 5152-5159. See Products 10274, 10318.

Near-Infrared Fluorescent Labeled Peptosome for Application to Cancer Imaging, Hiroki Tanisaka, Shinae Kizaka-Kondoh, Akira Makino, Shotaro Tanaka, masahiro Hiraoka, and Shunsaku Kimura, Bioconjugate Chem. 2008, 19, 109-117. DOI: 10.1021/bc7001665. See Product 10288.

Optimal Surface Chemistry for Peptide Immobilization in On-Chip Phosporylation Analysis, Kazuki Inamori, Motoki Kyo, Kazuki Matsukawa, Yusuke Inoue, Tatsuhiko Sonoda, Kenji Tatematsu, Katsuyuki Tanizawa, Takeshi Mori, and Yoshiki Katayama, Anal. Chem. 2008, 80, 643-650. DOI: 10.1021/ac701667g. See Product 10284.

Immobilized molecular beacons: A new strategy using UV-activated poly(methyl methacrylate) surfaces to provide large fluorescence sensitivities for reporting on molecular association events, Catherine Situma, Amanda J. Moehring, Mohamed A.F. Noor, Steven A. Soper, Analytical Biochemistry, 363, 2007, 35-45. DOI:10.1016/j.ab.2006.12.029. See Product 10287.

Antibody microarray-based profiling of complex specimens: systematic evaluation of labeling strategies, Wlad Kusnezow Virryan Banzon, Christoph Schroder, Rene Schaal, Jorg D. Hoheisel, Sven Ruffer, Petra Luft, Albert Duschl and Yana V. Syagailo, Protemics 2007, 7, 1786-1799. DOI: 10.1002/pmic.200600762. See Product 10200.

Carboxyl-Terminated Dendrimer-Coated Bioactive Interdace for Protein Microarray: High-Sensitivity Detection of Antigen in Complex Biological Samples, Parayil Kumaran Ajikumar, Jin Kiat Ng, Yew Chung Tang, Jim Yang Lee, Gregory Stephanopoulos, and Heng-Phon Too, Langmuir 2007, 23, 5670-5677. DOI: 10.1021/la063717u. See Product 10244.

Polyproline-Rod Approach to Isolating Protein Targets of Bioactive Small Molecules: Isolation of a New Target of Indomethacin, Shin-ichi Sato, Youngjoo Kwon, Shinji Kamisuki, Neeta Srivastava, Quian Mao, Yoshinori Kawazoe, and Motonari Uesugi, J. AM. CHEM. SOC. 2007, 129,873-880. DOI: 10.1021/ja0655643. See Products 10063, 10213, 10243, 10273.

Preparation of Biotinylated Cypridina Luciferase and Its Use in Bioluminescent Enzyme Immunoassay, Chun Wu, Kosei Kawasaki, Yoko Ogawa, Yasukazu Yoshida, Satoru Ohgiya, and Yoshihiro Ohmiya, Anal. Chem. 2007, 79, 1634-1638. DOI: 10.1021/ac061754k. See Product 10200.

Bioconjugation of Ln-Doped LaF₃ Nanoparticles to Avidin, Peter R. Diamente, Robert D. Burke, and Frank C. J. M. van Veggel, LangmuirI, 2006, 22, 1782-1788, LangmuirI, 2006, 22, 1782-1788. DOI: 10.1021/la052589r. See Product 10200.

Optimal Design of Microarray Immunoassays to Compensate for Kinetic Limitations, Wlad Kusnezow, Yana V. Syagailo, Sven Ruffer, Nina Baudenstiel, Christopher Gauer, Jorg D. Hoheisel, David Wild and Igor Goychuck, Molecular & Cellular Proteomics 5: 1681-1696, 2006. DOI: 10.1074/mcp.T500035-MCP200. See Product 10200.

The initial substrate-binding site of –secretase is located on presenilin near the active site, Anna Y. Kornilova, Frederic Bihel, Chittaranjan Das, and Michael S. Wolfe, PNAS March 1, 2005, vol. 102, no. 9. DOI; 10.1073/pnas.0407640102. See Product 10200.

A proof of the specificity of kanamycin-ribosomal RNA interaction with designed synthetic analogs and the antibacterial activity, Yoshio Nishimura, Hayamitsu Adachi, Motoki Kyo, Shoichi Murakami, Seiko Hattori, and Keiichi Ajito, Bioorganic & Medicinal Chemistry Letters 15 (2005) 2159-2162. DOI:10.1016/j.bmcl.2005.02.043. See Product 10284.

Label-Free Detection of Proteins in Crude Cell Lysate with Antibody Arrays by a Surface Plasmon Resonance Imaging Technique, Motoki Kyo, Kazue Usui-Aoki, and Hisashi Koga, Anal. Chem., 2005, 77 (22), pp 7115-7121. DOI: 10.1021/ac050884a. See Product 10249.

Electrogenerated Chemiluminescence. 77. DNA Hybridization Detection at High Amplification with [Ru(bpy)₃]²⁺-Containing Microspheres, Wujian Miao and Allen J. Bard, Anal. Chem. 2004, 76, 5379-5386. DOI: 10.1021/ac0495236. See Product 10193.

Surface-Immobilized Self Assembled Protein-Based Quantum Dot Nanoassemblies, Kim E. Sapsford, Igor L. Medintz, Joel P. Golden, Jeffery R. Deschamps, Harry Tetsuo Uyeda, and Heidi Mattoussi, Langmuir 2004, 20, 7720-7728. DOI: 10.1021/la049263n. See Product 10200.