t-boc-N-amido-dPEG®₁₂-OH

$225.00$900.00

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t-boc-N-amido-dPEG®12-OH, product number 10171, is a medium-length, monodispersed PEGylation reagent. This reagent terminates with alcohol on one end of the single molecular weight, discrete-length PEG (dPEG®) chain and a boc-protected amine on the other end. The dPEG® spacer is 38 atoms (42.7 Å) long. PN10171 is useful as a building block for other constructs that contain a short, discrete PEG in them.

About Quanta BioDesign’s dPEG® Products

Quanta BioDesign’s dPEG® products are single molecular weight PEG products with discrete chain lengths. Unlike polymer PEG products, our products have no dispersity; that is, they are monodispersed. Moreover, we do not purify our dPEG® products from a polymeric mixture. Instead, we synthesize our products from high purity starting materials. To learn more about our dPEG® technology, please click the links below:

What is dPEG®?

Frequently Asked Questions (about dPEG® products)

Using t-boc-N-amido-dPEG®12-OH

This product is useful for building unique constructs with dPEG® linkers. This product also permits supramolecular construction and unique side-chain modifications of amino acid residues in peptides.

The terminal alcohol of t-boc-N-amido-dPEG®12-OH transforms readily into different functional groups. Such transformations include aldehydes, azides, amines, and aliphatic alkynes. For example, reacting propargyl bromide with the terminal hydroxy group in the presence of a base forms a dPEG® product with an aliphatic alkyne for use in click chemistry reactions. Thus, t-boc-N-amido-dPEG®12-OH is a building block for new constructs that incorporate a discrete-length PEGylation product.

The boc-protected amine easily deprotects with trifluoroacetic acid or another acid. The exposed amine may be reacted further or left unmodified.

Bulk Quantities are Available

If you need bulk product in a larger package size than our standard sizes, please contact us for a quote. Our commercial capabilities permit us to manufacture this product at any scale that you need.

Buy It Now!

Please click the “Add to Cart” button now to purchase t-boc-N-amido-dPEG®12-OH. You, too, can discover “the dPEG® difference.”

Additional information

Weight .5 oz
Dimensions .75 × .75 × 2 in