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 SDS

Molecular Weight: 207.27; single compound

CAS: 85030-56-4

Spacers: dPEG® Spacer is 14 atoms and 15.5 Å

Shipping: Ambient

References: Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full overview of the dPEG® products.

De Novo Synthesis and Cellular Uptake of Organic Nanocapsules with Tunable Surface Chemistry. Kun Huang, Amy Jacobs, and Javid Rzayev. Biomacromolecules. 2011, 12 (6), pp 2327–2334. May 12, 2011. DOI: 10.1021/bm200394t.

Nanoscale Patterning of Surfaces via DNA Directed Spider Silk Assembly. Anton Molina, Thomas Scheibel, and Martin Humenik. Biomacromolecules. 2018. November 20, 2018. DOI: 10.1021/acs.biomac.8b01333.

FePt Nanoparticles as an Fe Reservoir for Controlled Fe Release and Tumor Inhibition. Chenjie Xu, Zhenglong Yuan, Nathan Kohler, Jaemin Kim, Maureen A. Chung and Shouheng Sun. J. Am. Chem. Soc. 2009, 131 (42) pp 15346–15351. October 1, 2009. DOI: 10.1021/ja905938a.

Size-Exclusion Properties of Nanoporous Films Derived from Polystyrene−Poly(methylmethacrylate) Diblock Copolymers Assessed Using Direct Electrochemistry of Ferritin. Yongxin Li and Takashi Ito. Anal. Chem. 2009, 81 (2) pp 851–855. December 10, 2008. DOI: 10.1021/ac802201w.

Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging. Ignacio Melgar-Asensio, Irawati Kandela, Fraser Aird, Soesiawati R. Darjatmoko, Cristobal de los Rios, Christine M. Sorenson, Daniel M. Albert, Nader Sheibani, and Jack Henkin. Investigative Opthalmology & Visual Science. 2018, 59 (10) pp 4071-4081. July 6, 2018. DOI: 10.1167/iovs.18-24087.

Benzene tricarboxamide derivatives with lipid and ethylene glycol chains self-assemble into distinct nanostructures driven by molecular packing, Nada Aljuaid a, Mark Tully b, Jani Seitsonen c, Janne Ruokolainen c and Ian W. Hamley, ChemComm, 2021, 57, 8360, 07/27/2021, DOI: 10.1039/d1cc03437e



Additional Search Phrases: PEG, dPEG, discrete PEG, polyethylene glycol, PEGylation reagent, m-PEG, mPEG, mPEG amine, PEG4, carboxyl reactive, active ester reactive, methoxy, methoxy capped, methoxy terminated, chemical modification reagent, chemical modification reagents, m-PEG4-amine, mPEG4-NH2, Methyl-PEG4-amine, MA(PEG)4, mPEG-amine

 SDS    Datasheet

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m-dPEG®₄-amine

$125.00 – $185.00

Clear
PRODUCT IS SOLD STRICTLY FOR INTERNAL LABORATORY AND RESEARCH PURPOSES ONLY AND HAS NOT BEEN REVIEWED BY THE FDA. PRODUCT IS NOT FOR RESALE AND CANNOT BE INCORPORATED INTO COMMERCIAL GOODS FOR ANY USE OR USED IN THE DEVELOPMENT OF COMMERCIAL PRODUCTS OR IN THE PERFORMANCE OF COMMERCIAL SERVICES UNLESS UNDER A SEPARATE LICENSING, SUPPLY, OR DISTRIBUTOR AGREEMENT WITH QUANTA BIODESIGN, LTD. For information pertaining to the commercial use of our products, please click here to contact us.

Email Sales@QuantaBioDesign.com for Bulk Pricing and Custom Syntheses
Product#: 10175 Categories: , , , , , Tags: , , , , , , , , , , , , , , ,

m-dPEG®4-amine, product number 10175, is a short, water-soluble, single molecular weight, discrete polyethylene glycol (dPEG®) chemical modification reagent. A methyl group terminates one end of the molecule. The reactive terminus opposite the methyl group is a primary amine. This product reacts with carboxylic acids and their active esters to form amide bonds.

For more information about Quanta BioDesign’s dPEG® technology, please visit our “What is dPEG®?” page. For answers to our most frequently asked questions, please click this link.

Uses of m-dPEG®4-amine

Several different published applications use m-dPEG®4-amine. These applications include the following:

  • development of synthetic, organic nanoparticles with tunable surface chemistry capable of enhancing cellular uptake;
  • site-specific modification of spider-silk-derived nanofibers;
  • improving the intravitreal residence time of nanoparticles for intraocular drug delivery and imaging; and,
  • creation of nanoporous films with size-exclusion properties.

Many other applications of m-dPEG®4-amine are possible. As long as carboxylic acids or their active esters are available for conjugation, conjugation of this product to nanoparticle surfaces and biomolecules can be accomplished readily.

Commercial Scale Production Is Available for m-dPEG®4-amine

If you need bulk product in a larger package size than our standard sizes, please contact us for a quote. Our commercial capabilities permit us to manufacture this product at any scale that you need.

Act Now

Quanta BioDesign offers dPEG®-based modification reagents that provide water solubility, improved hydrodynamic volume, no background noise (which means better signal), and no protein precipitation caused by aggregation. Why use anything else?

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Additional information

Weight.5 oz
Dimensions.75 × .75 × 2 in

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