Specs:

 SDS

Molecular Weight: 207.27; single compound

CAS: 85030-56-4

Spacers: dPEG® Spacer is 14 atoms and 15.5 Å

References: Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full overview of the dPEG® products.

De Novo Synthesis and Cellular Uptake of Organic Nanocapsules with Tunable Surface Chemistry. Kun Huang, Amy Jacobs, and Javid Rzayev. Biomacromolecules. 2011, 12 (6), pp 2327–2334. May 12, 2011. DOI: 10.1021/bm200394t.

FePt Nanoparticles as an Fe Reservoir for Controlled Fe Release and Tumor Inhibition. Chenjie Xu, Zhenglong Yuan, Nathan Kohler, Jaemin Kim, Maureen A. Chung and Shouheng Sun. J. Am. Chem. Soc. 2009, 131 (42) pp 15346–15351. October 1, 2009. DOI: 10.1021/ja905938a.

Size-Exclusion Properties of Nanoporous Films Derived from Polystyrene−Poly(methylmethacrylate) Diblock Copolymers Assessed Using Direct Electrochemistry of Ferritin. Yongxin Li and Takashi Ito. Anal. Chem. 2009, 81 (2) pp 851–855. December 10, 2008. DOI: 10.1021/ac802201w.

Additional Search Phrases: PEG, dPEG, discrete PEG, polyethylene glycol, PEGylation reagent, m-PEG, mPEG, mPEG amine, PEG4, carboxyl reactive, active ester reactive, methoxy, methoxy capped, methoxy terminated, chemical modification reagent, chemical modification reagents, m-PEG4-amine, mPEG4-NH2, Methyl-PEG4-amine, MA(PEG)4, mPEG-amine

m-dPEG®₄-amine

$125.00 – $185.00

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Product#: 10175 Categories: , , Tags: , , , , , , , , , , , , , , ,

m-dPEG®4-amine, product number 10175, is a short (14 atoms, 15.5 Å, long), water-soluble, single molecular weight, discrete polyethylene glycol (dPEG®) chemical modification reagent. A methyl group terminates one end of the molecule. The reactive terminus opposite the methyl group is a primary amine. This product reacts with carboxylic acids and their active esters to form amide bonds.

For more information about Quanta BioDesign’s dPEG® technology, please visit our “What is dPEG®?” page. For answers to our most frequently asked questions, please click this link.

Uses of m-dPEG®4-amine

Several different published applications use m-dPEG®4-amine. These applications include the following:

  • development of synthetic, organic nanoparticles with tunable surface chemistry capable of enhancing cellular uptake;
  • site-specific modification of spider-silk-derived nanofibers;
  • improving the intravitreal residence time of nanoparticles for intraocular drug delivery and imaging; and,
  • creation of nanoporous films with size-exclusion properties.

Many other applications of m-dPEG®4-amine are possible. As long as carboxylic acids or their active esters are available for conjugation, conjugation of this product to nanoparticle surfaces and biomolecules can be accomplished readily.

Commercial Scale Production Is Available for m-dPEG®4-amine

If you need bulk product in a larger package size than our standard sizes, please contact us for a quote. Our commercial capabilities permit us to manufacture this product at any scale that you need.

Act Now

Quanta BioDesign offers dPEG®-based modification reagents that provide water solubility, improved hydrodynamic volume, no background noise (which means better signal), and no protein precipitation caused by aggregation. Why use anything else?

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Additional information

Weight .5 oz
Dimensions .75 × .75 × 2 in

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