SDSMolecular Weight: 588.67; single compound
CAS: 459426-22-3
Purity: > 98%
Spacers: dPEG® Spacer is 16 atoms and 19.2 Å
Shipping: Ambient
References: Greg T. Hermanson, Bioconjugate Techniques, 2nd Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0). Specifically see pp. 726-730 in his chapter 18 on discrete PEG compounds for pegylation applications.
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.
Preparation of Biotinylated Cypridina Luciferase and Its Use in Bioluminescent Enzyme Immunoassay. Chun Wu, Kosei Kawasaki, Yoko Ogawa, Yasukazu Yoshida, Satoru Ohgiya, and Yoshihiro Ohmiya. Analytical Chemistry. 2007, 79 (4), pp 1634–1638. January 13, 2007. DOI: 10.1021/ac061754k.
Kinetics of Amine Modification of Proteins. George P. Smith. Bioconjugate Chemistry. 2006, 17 (2), pp 501–506. February 16, 2006. DOI: 10.1021/bc0503061.
Intermolecular Interaction of Avidin and PEGylated Biotin. Shan Ke, John C. Wright, and Glen S. Kwon. Bioconjugate Chemistry. 2007, 18 (6), pp 2109–2114. October 19, 2007. DOI: 10.1021/bc700204k.
Surface-Immobilized Self-Assembled Protein-Based Quantum Dot Nanoassemblies. Kim E. Sapsford, Igor L. Medintz, Joel P. Golden, Jeffery R. Deschamps, Harry Tetsuo Uyeda, and Heidi Mattoussi. Langmuir. 2004, 20 (18), pp 7720–7728. August 6, 2004. DOI: 10.1021/la049263n.
Bioconjugation of Ln3-Doped LaF3 Nanoparticles to Avidin. Peter R. Diamente, Robert D. Burke, and Frank C. J. M. van Veggel. Langmuir. 2006, 22 (4), pp 1782–1788. December 30, 2005. DOI: 10.1021/la052589r.
Optimal Design of Microarray Immunoassays to Compensate for Kinetic Limitations. Wlad Kusnezow, Yana V. Syagailo, Sven Ruffer, Nina Baudenstiel, Christopher Gauer, Jorg D. Hoheisel, David Wild and Igor Goychuck. Molecular & Cellular Proteomics. 2006, (5) pp 1681-1696. May 30, 2006. DOI: 10.1074/mcp.T500035-MCP200.
Antibody microarray-based profiling of complex specimens: systematic evaluation of labeling strategies. Wlad Kusnezow Virryan Banzon, Christoph Schroder, Rene Schaal, Jorg D. Hoheisel, Sven Ruffer, Petra Luft, Albert Duschl and Yana V. Syagailo. Protemics. 2007, 11 (7), pp 1786-1799. March 2, 2007. DOI: 10.1002/pmic.200600762.
Biomimetic approach to the formation of gold nanoparticle/silica core/shell structures and subsequent bioconjugation. Sung Min Kang, Kyung-Bok Lee, Dong Jin Kim and Insung S Choi. Nanotechnology. 2006, 17 (18), pp 4719–4725. September 1, 2006. DOI: 10.1088/0957.
The initial substrate-binding site of y–secretase is located on presenilin near the active site. Anna Y. Kornilova, Frederic Bihel, Chittaranjan Das, and Michael S. Wolfe. PNAS. 2005, 102 (9), pp 3230-3235. March 1, 2005. DOI: 10.1073/pnas.0407640102.
On-Bead Screening of Combinatorial Libraries: Reduction of Nonspecific Binding by Decreasing Surface Ligand Density. Xianwen Chen, Pauline H. Tan, Yanyan Zhang and Dehua Pei. J. Combinatorial Science. 2009, 11 (4), pp 604-611. April 28, 2009. DOI: 10.1021/cc9000168.
Structural Characterization of Individual Vesicles using Fluorescence Microscopy. Emily C. Heider, Moussa Barhoum, Kyle Edwards, Karl-Heinz Gericke, and Joel M. Harris. Analytical Chemistry. 2011, 83 (12), pp 4909–4915. May 16, 2011. DOI: 10.1021/ac200632h.
Preparation, characterization, resistance to protein adsorption, and specific avidin–biotin binding of poly(amidoamine) dendrimers functionalized with oligo (ethylene glycol) on gold. Chi Ming Yam , Maxence Deluge, David Tang, Amit Kumar, Chengzhi Cai. Journal of Colloid and Interface Science. 2006, 296 (1), pp 118–130. April 2006. DOI :10.1016/j.jcis.2005.08.052.
Kinetics of G-protein–coupled receptor endosomal trafficking pathways revealed by single quantum dots. Katye M. Fichter, Marc Flajolet, Paul Greengard and Tania Q. Vu. PNAS. 2010, 107 (43), pp 18658-18663. October 26, 2010. DOI: 10.1073/pnas.1013763107.
Identification and characterization of alternative splice variants of the mouse Trek2/Kcnk10 gene. K. Mirkovic and K. Wickman. Neuroscience. 2011, 194 (1), pp 11-18 October 27, 2011. DOI: 10.1016/j.neuroscience.2011.07.064.
From SOMAmer-Based Biomarker Discovery to Diagnostic and Clinical Applications: A SOMAmer-Based, Streamlined Multiplex Proteomic Assay. Stephan Kraemer, Jonathan D. Vaught, Christopher Bock, Larry Gold, Evaldas Katilius, Tracy R. Keeney, Nancy Kim, Nicholas A. Saccomano, Sheri K. Wilcox, Dom Zichi, Glenn M. Sanders. PLoS ONE. 6 (10), e26332. October 17, 2011. DOI:10.1371/journal.pone.0026332.
Generation of Monoclonal Antibodies to the AML1-ETO Fusion Protein: Strategies for Overcoming High Homology. Stephen G. Simkins, Steven L. Knapp, George H. Brough, Karen L. Lenz, Lise Barley-Maloney, Jeffrey P. Baker, Liesbeth Dekking, Hobert Wai, and Eric P. Dixon. Hybridoma. 2011, 30 (5), pp 433-443, Oct. 18, 2011. DOI: 10.1089/hyb.2011.0037.
Evaluation of substrate and inhibitor binding to yeast and human isoprenylcysteine carboxyl methyltransferases (Icmts) using biotinylated benzophenone-containing photoaffinity probes. Kalub Hahne, Jeffery S.Vervacke, Liza Shrestha, James L. Donelson, Richard A.Gibbs, Mark D. Distefano, Christine A. Hrycyna. Biochemical and Biophysical Research Communications. 2012, 423 (1), pp 98-103. June 22, 2012. DOI: 10.1016/j.bbrc.2012.05.089.
Expression of active human sialyltransferase ST6GalNAcI in Escherichia coli. Georgios Skretas, Sean Carroll, Shawn DeFrees, Marc F Schwartz, Karl F Johnson and George Georgiou. Microbial Cell Factories. 2009 8 (50) September 30, 2009. DOI: 10.1186/1475-2859-8-50.
Aptamer-Based Molecular Recognition of Lysergamine, Metergoline and Small Ergot Alkaloids. Elsa Rouah-Martin, Jaytry Mehta, Bieke van Dorst, Sarah de Saeger, Peter Dubruel, Bert U. W. Maes, Filip Lemiere, Erik Goormaghtigh, Devin Daems, Wouter Herrebout, François van Hove, Ronny Blust and Johan Robbens. International Journal of Molecular Sciences. 2012, 13 (12) pp 17138-17159. December 14, 2012. DOI:10.3390/ijms131217138.
Determination of bacterial viability by selective capture using surface-bound siderophores. Mark L. Wolfenden, Rama M. Sakamuri, Aaron S. Anderson, Lakshman Prasad, Jurgen G. Schmidt, Harshini Mukundan. Advances in Biological Chemistry. 2012, 2 (4) pp 396-402. September 30, 2012. DOI: 10.4236/abc.2012.24049.
Biotin-end-functionalized highly fluorescent water-soluble polymers. Paula Relogio, Mael Bathfield, Zofia Haftek-Terreau, Mariana Beija, Arnaud Favier, Marie-Josephe Giraud-Panis, Franck D'Agosto, Bernard Mandrand, Jose Paulo S. Farinha, Marie-Therese Charreyre and Jose M. G. Martinho. Polymer Chemistry. 2013, 4 (10), pp 2968-2981. February 22, 2013. DOI: 10.1039/c3py00059a.
Bioconjugation of Ln3+-Doped LaF3 Nanoparticles to Avidin. Peter R. Diamente, Robert D. Burke, and Frank C. J. M. van Veggel. Langmuir. 2006, 22 (4) pp 1782–1788. December 30, 2005. DOI: 10.1021/la052589r.
Psoralen Conjugates for Visualization of Genomic Interstrand Cross-Links Localized by Laser Photoactivation. Arun Kalliat Thazhathveetil, Su-Ting Liu, Fred E. Indig, and Michael M. Seidman. Bioconjugate Chemistry. 2007, 18 (2) pp 431–437. January 9, 2007. DOI: 10.1021/bc060309t.
Entwicklung von Antikörper-Mikroarray: von Biophysik der Mikrospot-Reaktion bis zur Hochdurchsatzanalyse der Proteine. Vorgelegt von Wals Kusnezow, Nishnij, Ural and Russische Foderation. Proteomics 2005, 6 pp 1-285 June 27, 2005. DOI: 10.1002/pmic.200500149.
A novel immunotherapy for superficial bladder cancer by intravesical immobilization of GM-CSF. Zhiming Hu, Wanlong Tan, Lin Zhang, Zhongkun Liang, Cuixiang Xu , Hua Su, Jianxin Lu, Jimin Gao. Journal of Cellular and Molecular Medicine. 2010, 14 (6b) pp 1836-1844. July 20, 2009. DOI: 10.1111/j.1582-4934.2009.00818.x.
A novel method for quantitative measurement of a therapeutic monoclonal antibody in the presence of its target protein using enzymatic digestion. Julie Doucet, Alexandre Avrameas. Journal of Pharmaceutical and Biomedical Analysis. 2010, 52 (4) pp 565–570. August 1, 2010. DOI:10.1016/j.jpba.2010.01.033.
A single step multiplex immunofluorometric assay for differential diagnosis
of BSE and scrapie. Yue Tang ,Jemma Thorne, Kirsty Whatling , Jorg G. Jacobs, Jan Langeveld, Maurice J. Sauer. Journal of Immunological Methods. 2010, 356 (1-2) pp 29–38. April 30, 2010. DOI:10.1016/j.jim.2010.03.002.
Bioengineered surfaces to improve the blood compatibility of biomaterials through direct thrombin inactivation. S.C. Freitas, T.B. Cereija, A.C. Figueiredo, H. Osório P.J.B. Pereira, M.A. Barbosa, M.C.L. Martins. Acta Biomaterialia. 2012, 8 (11) pp 4101–4110. November 2012. DOI:10.1016/j.actbio.2012.07.020.
Increased cytochrome c in rat cerebrospinal fluid after cardiac arrest and its effects on hypoxic neuronal survival. Hao Liua, Syana M. Sarnaikc, Mioara D. Manolec, Yaming Chend, Sunita N. Shindeb, Wenjin Li, Marie Rosea, Henry Alexandere, Jie Chenb, Robert S.B. Clarkd, Steven H. Grahama, Robert W. Hickey. Resuscitation. 2012, 83 (12) pp 1491– 1496. December 2012. DOI: 10.1016/j.resuscitation.2012.04.009.
Multifaceted Activities of Seven Nanobodies against Complement C4b. Karla I De la O Becerra, Wout Oosterheert, Ramon M van den Bos, Katerina T Xenaki, Joseph H Lorent, Maartje Ruyken, Arie Schouten, Suzan H M Rooijakkers, Paul M P van Bergen en Henegouwen, and Piet Gros. The Journal of Immunology. 2022. Vol 208, Issue 9. May 1, 2022. https://doi.org/10.4049/jimmunol.2100647.
Development and characterization of rabbit monoclonal antibodies that recognize human spermine oxidase and application to immunohistochemistry of human cancer tissues. Armand W J W Tepper, Gerald Chu,Vincent N A Klaren, Jay H Kalin, Patricia Molina-Ortiz, Antonietta Impagliazzo. Plos One, 2022, April 22, 2022, https://doi.org/10.1371/journal.pone.0267046.
Hepcidin is potential regulator fo renin activity. Jaakko Piesanen , Jarkko Valjakka , Sanna Niemelä, Marjut Borgenström, Seppo Nikkari, Vesa Hytönen, Juha Määttä, Tarja Kunnas. Plos One. 2022. April 20, 2022. https://doi.org/10.1371/journal.pone.0267343.
Additional Search Phrases: NHS-dPEG4-biotin, PEG, dPEG, discrete PEG, polyethylene glycol, poly (ethylene glycol), Quanta, Quanta BioDesign, PEGylation reagent, NHS biotin, NHS-biotin, biotin NHS ester, biotinylation, biotinylate, biotinylated, biotin, biotin-NHS, biotin NHS, N-hydroxysuccinimide, active ester, amine reactive, biotinylation reagent, biotinylation reagents, biotin PEG, PEG biotin, NHS PEG biotin, biotin PEG NHS, PEG4, NHS LC biotin, biotin LC NHS, LC biotin NHS, NHS-LC-biotin, biotin-LC-NHS, LC-biotin, LC biotin replacement, PEG4, biotin label, cell labeling, label cells, Biotin-PEG4-NHS ester, PEG4-biotin, NHS-PEG4-biotin, Biotin-PEG-NHS ester