$150.00 – $1,200.00
TFP-dPEG®4-biotinidase-resistant biotin is a water-soluble biotinylation reagent that has been modified to resist hydrolysis by biotinidase (EC 184.108.40.206). This product combines Biotinoyl-2-aminobutyric acid, with the 2,3,5,6-tetrafluorophenyl (TFP) ester of a single molecular weight, discrete polyethylene glycol (dPEG®) linker. TFP-dPEG®4-biotinidase-resistant biotin has biotin’s typical high affinity for avidin and streptavidin. However, the modified biotin prevents recycling by biotinidase. This product is useful in applications such as ELISAs of tissue samples and antibody pretargeting, where endogenous biotinidase potentially can recycle biotin.