NHS-biotin

$50.00$150.00

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PRODUCT IS SOLD STRICTLY FOR INTERNAL LABORATORY AND RESEARCH PURPOSES ONLY AND HAS NOT BEEN REVIEWED BY THE FDA. PRODUCT IS NOT FOR RESALE AND CANNOT BE INCORPORATED INTO COMMERCIAL GOODS FOR ANY USE OR USED IN THE DEVELOPMENT OF COMMERCIAL PRODUCTS OR IN THE PERFORMANCE OF COMMERCIAL SERVICES UNLESS UNDER A SEPARATE LICENSING, SUPPLY, OR DISTRIBUTOR AGREEMENT WITH QUANTA BIODESIGN, LTD. For information pertaining to the commercial use of our products, please click here to contact us.

Email Sales@QuantaBioDesign.com for Bulk Pricing and Custom Syntheses

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NHS-biotin, product number 10205, is a classic, non-dPEG® biotinylation reagent. Biotin (5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid, CAS number 58-85-5) is a water-soluble vitamin. A wide range of biotechnology and clinical applications use biotin. NHS-biotin (2,5-dioxopyrrolidin-1-yl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate, CAS number 35013-72-0) is the N-hydroxysuccinimide ester of biotin. The NHS ester is reactive with free primary amines. NHS-biotin is useful for labeling proteins, peptides, surfaces (such as silica, glass, or magnetic particles) coated with primary amines, and the like. It can also be used with amine-terminated dPEG® products to create novel biotinylated dPEG® products.

NHS-biotin, product number 10205, is not soluble in water, but the NHS ester will hydrolyze if the product gets wet. The optimal storage temperature of NHS-biotin is -20°C. When removed from storage, PN10205 should be allowed to equilibrate fully to ambient temperature before opening the bottle. The product always should be handled to minimize exposure to moisture. NHS-biotin dissolves in N,N’-dimethylacetamide (DMAC) or dimethylsulfoxide (DMSO). DMAC and DMSO must be dried over 3Å molecular sieves for at least 24 hours before use. Solutions of NHS-biotin must be used immediately. The storage of NHS-biotin in solution is not recommended.

If you need bulk product in a larger package size than our standard sizes, please contact us for a quote. Our commercial capabilities permit us to manufacture this product at any scale that you need.

Additional information

Weight .5 oz
Dimensions .75 × .75 × 2 in