Specs:

 SDS

Molecular Weight: 660.64; single compound

CAS: 1301738-40-8

Spacers: Spacer is 17 and 21 atoms and 19.1 and 19.6 Å, resp.

References: Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Mono-PEGylated Dimeric Exendin-4 as High Receptor Binding and Long-Acting Conjugates for Type 2 Anti-Diabetes Therapeutics.Tae Hyung Kim, Hai Hua Jiang, Seulki Lee, Yu Seok Youn, Chan Woong Park,Youngro Byun, Xiaoyuan Chen, and Kang Choon Lee. Bioconjugate Chem. 2011, 22 (4), pp 625–632. March 14, 2011. DOI: 10.1021/bc100404x.

Reorienting the Fab Domains of Trastuzumab Results in Potent HER2 Activators. Justin M. Scheer, Wendy Sandoval, J. Michael Elliott, Lily Shao, Elizabeth Luis, Sock-Cheng Lewin-Koh, Gabriele Schaefer, Richard Vandlen. PLOS ONE. 2012, 7 (12) e51817. December 20, 2012. DOI: 10.1371/journal.pone.0051817.




Additional Search Phrases: Bis-Maleimide amine,TFA salt, bis mal amine, 1301738408, PEG, dPEG, discrete PEG, polyethylene glycol, PEGylation reagent, crosslinker, cross linker, crosslinking reagent, amine reactive, homobifunctional, maleimide, maleimido, thiol, thiol reactive, bis-maleimide, bis-MAL, lysine, trifluoroacetic acid, trifluoroacetate, TFA, TFA salt


Bis-Maleimide amine,TFA salt

$225.00 – $750.00

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Product#: 10232 Categories: , ,

Bis-Maleimide amine, TFA salt, product number 10232, is a crosslinking product. The core of the molecule is the amino acid lysine. Maleimido-propanoate modifies both the α and ε amino groups of lysine. Diaminohexane converts the carboxylic acid of lysine to an amine (as a TFA salt). This is not a dPEG® product; however, it can react with the carboxylic acid termini of dPEG® products to form new products.

Bis-Maleimide amine, TFA salt, is designed to bridge disulfide bonds. The spacer length from maleimide reactive site through the α-amino group to the terminal amine-TFA salt is 17 atoms and 19.1 Å. The spacer length from the maleimide double bond through the ε-amino group to the terminal amine-TFA salt is 21 atoms and 19.6 Å.

Additional information

Weight .5 oz
Dimensions .75 × .75 × 2 in

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