Specs:

 SDS

Molecular Weight: 369.45; single compound

CAS: 352439-37-3

Purity: > 98%

Spacers: dPEG® Spacer is 28 atoms and 32.1 Å

Shipping: Ambient

References: Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

How a grafting anchor tailors cellular uptake and in vivo fate of dendronized iron oxide nanoparticles. C. Bordeianu, A. Parat, C. Affolter-Zbaraszczuk, R. N. Muller, S. Boutry, S. Begin-Colin, F. Meyer, S. Laurent, and D. Felder-Flesch. Journal of Materials Chemistry B. 2017, 2013 (00) pp 1-3. May 26, 2017. DOI: 10.1039/C7TB00781G.

Confocal imaging to quantify passive transport across biomimetic lipid membranes. Su Li, Peichi Hu, and Noah Malmstadt. Analytical Chemistry. 2010, 82 (18) pp 7766-7771. September 15, 2010. DOI: 10.1021/ac1016826.

Label-free electrical detection of pyrophosphate generated from DNA polymerase reactions on field-effect devices. Grace M. Credo, Xing Su, Kai Wu, Oguz H. Elibol, David J. Liua, Bobby Reddy Jr., Ta-Wei Tsai, Brian R. Dorvel, Jonathan S. Daniels, Rashid Bashir, and Madoo Varma. Analyst. 2012 137 (6) pp 1351-1362. March 21, 2012. DOI:10.1039/c2an15930a.

Quantum Dots with Multivalent and Compact Polymer Coatings for Efficient Fluorescence Resonance Energy Transfer and Self-Assembled Biotagging. Hongwei Duan , Min Kuang and Y. Andrew Wang. Chemistry of Materials. 2010, 22 (15) pp 4372–4378. July 13, 2010. DOI: 10.1021/cm100442x.




Additional Search Phrases:

Amino-dPEG8-OH, 352439373, PEG, dPEG, discrete PEG, polyethylene glycol, PEGylation reagent, amino alcohol, amine, hydroxyl, alcohol, carboxyl reactive, chemical modification, Amino-PEG8-OH, Amino-PEG8-alcohol, Hydroxy-PEG8-amine, Amino-PEG-alcohol



 SDS    Datasheet

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Amino-dPEG®₈-OH

$150.00 – $300.00

Clear
PRODUCT IS SOLD STRICTLY FOR INTERNAL LABORATORY AND RESEARCH PURPOSES ONLY AND HAS NOT BEEN REVIEWED BY THE FDA. PRODUCT IS NOT FOR RESALE AND CANNOT BE INCORPORATED INTO COMMERCIAL GOODS FOR ANY USE OR USED IN THE DEVELOPMENT OF COMMERCIAL PRODUCTS OR IN THE PERFORMANCE OF COMMERCIAL SERVICES UNLESS UNDER A SEPARATE LICENSING, SUPPLY, OR DISTRIBUTOR AGREEMENT WITH QUANTA BIODESIGN, LTD. For information pertaining to the commercial use of our products, please click here to contact us.

Email Sales@QuantaBioDesign.com for Bulk Pricing and Custom Syntheses
Product#: 10240 Categories: , , , ,

Amino-dPEG®8-OH is a monodisperse PEGylation reagent designed for chemical modification of biomolecules and surfaces. The primary amine on one end of the molecule reacts with carboxylates to form amide bonds and with aldehydes and ketones to form labile Schiff bases. The hydrophilic, non-immunogenic dPEG® spacer improves water solubility and increases the hydrodynamic volume of conjugates. The terminal hydroxy can be modified to add different functional groups.

How do I use Amino-dPEG®8-OH?

Amino-dPEG®8-OH has many possible uses. The most common uses are modifying biomolecules and passivating surfaces with an extremely hydrophilic coating. The primary amine on one end of the dPEG® linker reacts with carboxylates, aldehydes, and ketones. Conjugations with this molecule most commonly use the amine-carboxylate reaction because it forms stable amide bonds. A carbodiimide such as EDC directly connects the amino group to a carboxylate. Alternatively, activation of carboxylate as the NHS or TFP ester followed by reaction under slightly basic conditions also permits conjugation of the carboxylate and amino moieties.

The amino group also reacts with aldehydes and ketones to form Schiff bases. Schiff bases are reducible to secondary amines for improved stability.

The published uses of Amino-dPEG®8-OH include the following:

  • Surface coating of iron oxide nanoparticles;
  • Surface coating of quantum dots;
  • Development of a confocal imaging system to measure passive transport across membranes; and,
  • Development of a label-free detector of pyrophosphate.

Is Commercial Scale Production of Amino-dPEG®8-OH Available?

Yes, it is. If you need bulk product in a larger package size than our standard sizes, please contact us for a quote. Our commercial capabilities permit us to manufacture this product at any scale that you need.

Buy It Now!

Amino-dPEG®8-OH is a highly pure monodisperse PEGylation reagent that offers excellent performance in a variety of applications. For over 20 years, we have led the industry in price, quality, performance, and innovation of monodisperse, discrete PEG linkers and spacers. Why look anywhere else?

Click the “Add to Cart” button now to buy this product and discover the dPEG® difference.

Additional information

Weight .5 oz
Dimensions .75 × .75 × 2 in

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