Specs:

 SDS

Molecular Weight: 193.24; single compound

CAS: 86770-74-3

Purity: > 98%

Spacers: dPEG® Spacer is 13 atoms and 14.3 Å

Shipping: Ambient

References: Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Label-Free Detection of Proteins in Crude Cell Lysate with Antibody Arrays by a Surface Plasmon Resonance Imaging Technique. Motoki Kyo, Kazue Usui-Aoki, and Hisashi Koga. Analytical Chemistry. 2005, 77 (22), pp 7115–7121. October 18, 2005. DOI: 10.1021/ac050884a.

Development of an oligo (ethylene glycol)-based SPR immunosensor for TNT detection. Yutaka Mizuta, Takeshi Onodera, Praveen Singh, Kiyoshi Matsumoto, Norio Miura, Kiyoshi Toko. Biosensors and Bioelectronics. 2008, 24 (2), pp 191-197. October 15, 2008. DOI:10.1016/j.bios.2008.03.042.

Real-Time Video Imaging of Protease Expression In Vivo. Lei Zhu, Jin Xie, Magdalena Swierczewska, Fan Zhang, Qimeng Quan, Ying Ma, Xuexun Fang, Kwangmeyung Kim, Seulki Lee, Xiaoyuan Chen. Theranostics. 2011, (1) pp 18-27. January 12, 2011. http://www.thno.org/v01p0018.htm.

Confocal imaging to quantify passive transport across biomimetic lipid membranes. Su Li, Peichi Hu, and Noah Malmstadt. Analytical Chemistry. 2010, 82 (18) pp 7766-7771 September 15, 2010. DOI: 10.1021/ac1016826.

Label-free electrical detection of pyrophosphate generated from DNA polymerase reactions on field-effect devices. Grace M. Credo, Xing Su, Kai Wu, Oguz H. Elibol, David J. Liua, Bobby Reddy Jr., Ta-Wei Tsai, Brian R. Dorvel, Jonathan S. Daniels, Rashid Bashir, and Madoo Varma. Analyst. 2012, 137 (6) pp 1351-1362. March 21, 2012. DOI:10.1039/c2an15930a.

Synthesis of Biotinylated r-D-Mannoside or N-Acetyl _-D-Glucosaminoside Decorated Gold Nanoparticles: Study of Their Biomolecular Recognition with Con A and WGA Lectins. Xiaoze Jiang, Abdelghani Housni, Guillaume Gody, Paul Boullanger, Marie-The´re`se Charreyre, Thierry Delair, and Ravin Narain. Bioconjugate Chem. 2010, 21 pp 521–530. February 3, 2010. DOI: 10.1021/bc900431p.

Surface Chemical Functionalization of Cylindrical Nanopores Derived from a Polystyrene−Poly(methylmethacrylate) Diblock Copolymer via Amidation. Yongxin Li and Takashi Ito. Langmuir. 2008, 24 (16) pp 8959–8963. July 1, 2008. DOI: 10.1021/la800992f.

Permeation Studies across Symmetric and Asymmetric Membranes in Microdroplet Arrays. Simon Bachler, Marion Ort, Stefanie D. Krämer, and Petra S. Dittrich. Analytical Chemistry. 2021. Volume 93, 12, 5137-5144. 03/31/2021. https://doi.org/10.1021/acs.analchem.0c04939





Additional Search Phrases:

Amino-dPEG4-OH, 86770743, PEG, dPEG, discrete PEG, polyethylene glycol, PEGylation reagent, amino alcohol, amine, hydroxyl, alcohol, carboxyl reactive, chemical modification, Amino-PEG4-OH, Amino-PEG4-alcohol, Hydroxy-PEG4-amine, Amino-PEG-alcohol



 SDS    Datasheet

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Amino-dPEG®₄-OH

$100.00 – $150.00

Clear
PRODUCT IS SOLD STRICTLY FOR INTERNAL LABORATORY AND RESEARCH PURPOSES ONLY AND HAS NOT BEEN REVIEWED BY THE FDA. PRODUCT IS NOT FOR RESALE AND CANNOT BE INCORPORATED INTO COMMERCIAL GOODS FOR ANY USE OR USED IN THE DEVELOPMENT OF COMMERCIAL PRODUCTS OR IN THE PERFORMANCE OF COMMERCIAL SERVICES UNLESS UNDER A SEPARATE LICENSING, SUPPLY, OR DISTRIBUTOR AGREEMENT WITH QUANTA BIODESIGN, LTD. For information pertaining to the commercial use of our products, please click here to contact us.

Email Sales@QuantaBioDesign.com for Bulk Pricing and Custom Syntheses
Product#: 10249 Categories: , , , ,

Amino-dPEG®4-OH, product number 10249, also known as Amino-dPEG®4-alcohol, is a short, monodisperse PEGylation reagent. This non-immunogenic, single molecular weight polyethylene glycol (PEG) reagent has a discrete-length chain. Therefore, it is sold under the dPEG® tradename. By reacting the amine end of this product with free carboxylates, this extremely hydrophilic PEGylation reagent modifies biomolecules and surfaces with appropriate functional groups.

PEGylation with dPEG® Products

Typical PEGylation reagents are disperse polymers. Such polymers are complex mixtures of different chain lengths and molecular weights. Conjugates made with non-uniform polymers are challenging to analyze.

In contrast, Quanta BioDesign’s dPEG® products are single molecular weight products with discrete PEG chain lengths. Although our products are monodispersed, we do not purify PEG from a polymer mixture. Instead, we synthesize our products as single molecules from high purity starting materials. Consequently, our monodisperse PEGylation reagents are superior to other types of PEGylation reagents.

Learn more!

What is dPEG®?

Frequently Asked Questions (about dPEG® products)

For What Applications is Amino-dPEG®4-OH Used?

This product has many possible uses. The primary amine on one end of the molecule reacts with carboxylates to form amide bonds. Also, it reacts with aldehydes or ketones to form Schiff bases that are reducible to secondary amines. The most popular use for this product is the passivation of carboxylate-functionalized surfaces. The terminal alcohol of the PEG chain is non-immunogenic and imparts hydrophilicity to the conjugate molecule or surface. Consequently, conjugate molecules are water-soluble. Moreover, when used to passivate surfaces, Aminod-dPEG®4-OH reduces or eliminates non-specific binding.

Amino-dPEG®4-OH appears several times in published scientific literature. Applications of this product include:

  • modification and passivation of nanoparticle surfaces;
  • development of SPR sensors;
  • development of a confocal imaging system; and,
  • development of an electric field sensor for DNA polymerase.

Commercial Scale Production of Amino-dPEG®4-OH is Available

If you need bulk product in a larger package size than our standard sizes, please contact us for a quote. Our commercial capabilities permit us to manufacture this product at any scale that you need.

Buy It Now!

Amino-dPEG®4-OH is a highly pure monodisperse PEGylation reagent that offers excellent performance in a variety of applications. Our prices are competitive across the industry. Why buy an inferior product? Why pay more from someone else for this product?

Click the “Add to Cart” button now to buy this product and discover the dPEG® difference.

Additional information

Weight .5 oz
Dimensions .75 × .75 × 2 in

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