t-boc-N-amido-dPEG®₄-OH

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t-boc-N-amido-dPEG®4-OH, product number 10250, is a short (13 atoms, 14.3 Å), monodispersed PEGylation reagent. The reagent terminates with alcohol on one end of the single molecular weight, discrete-length PEG (dPEG®) chain and a boc-protected amine on the other end. This compound is a building block that permits other constructs with a short, discrete PEG in them.

Using Quanta BioDesign’s dPEG® Products

Quanta BioDesign’s dPEG® products are single molecular weight PEG products with discrete chain lengths. Unlike polymer PEG products, our products have no dispersity; that is, they are monodispersed. Moreover, we do not purify our dPEG® products from a polymeric mixture. Instead, we synthesize our products from high purity starting materials. To learn more about our dPEG® technology, please click the links below:

What is dPEG®?

Frequently Asked Questions (about dPEG® products)

Using t-boc-N-amido-dPEG®4-OH

This product is useful for building novel constructs with dPEG® linkers. This product also permits supramolecular construction and unique side-chain modifications of amino acid residues in peptides.

The terminal alcohol of t-boc-N-amido-dPEG®4-OH can be transformed easily into a different functional group such as an aldehyde or acid. Moreover, the hydroxy group reacts with halide-functionalized compounds to form new products. For example, by reacting propargyl bromide with the terminal hydroxy group in the presence of a base, a dPEG® product with an aliphatic alkyne is formed. Thus, t-boc-N-amido-dPEG®4-OH is a building block for new constructs that incorporate a discrete-length PEGylation product.

The boc-protected amine easily deprotects with trifluoroacetic acid or another acid. The exposed amine may be reacted further or left unmodified.

Bulk Quantities are Available

If you need bulk product in a larger package size than our standard sizes, please contact us for a quote. Our commercial capabilities permit us to manufacture this product at any scale that you need.

Buy It Now!

Please click the “Add to Cart” button now to purchase t-boc-N-amido-dPEG®4-OH. You, too, can discover “the dPEG® difference.”

Additional information

Weight .5 oz
Dimensions .75 × .75 × 2 in