Description
Specs:
SDS
Molecular Weight: 509.54; single compound
CAS: 756525-90-3
Purity: > 97%
Spacers: dPEG® Spacer is 26 atoms and 29.8 Å
Shipping: Ambient
References: Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.
Short polyethylene glycol chains densely bound to soft nanotube channels for inhibition of protein aggregation. N. Kameta, T. Matsuzawa, K. Yaoi, and M. Masuda. RSC Advances. 2016, 6 (43) pp 36744-36750. April 7, 2016. DOI: 10.1039/C6RA06793J.
Laser-Activated Gene Silencing via Gold Nanoshell-siRNA Conjugates,Gary B Braun, Alessia Pallaoro, Guohui Wi, Dimitris Missirlis, Joseph A. Zasadzinski, Matthew Tirrell, and Norbert O. Reich. ACS Nano. 2009, 3 (7), pp 2007–2015. June 15, 2009. DOI:10.1021/nn900469q.
Hairpin Structure of a Biarsenical- Tetracysteine Motif Determined by NMR Spectroscopy, Fatemeh Madani, Jesper Lind, Peter Damberg, Stephen R. Adams, Roger Y. Tsien, and Astrid O. Graslund. JACS. 2009, 131 (13), pp 4613–4615. March 12, 2009. DOI: 10.1021/ja809315x.
Potent D-peptide inhibitors of HIV-1 entry, Brett D. Welch, Andrew P. VanDemark, Annie Heroux, Christopher P. Hill, and Michael S. Kay. PNAS. 2007, 43 (104), pp 16828-16833. October 23, 2007. DOI: 10.1073/pnas.0708109104.
Improved pharmacokinetics and immunogenicity profile of organophosphorus hydrolase by chemical modification with polyethylene glycol. Boris N. Novikov, Janet K. Grimsley, Rory J. Kern, James R. Wild, Melinda E. Wales. Elsevier. 2010, 3 (146) pp 318-325. September 15, 2010. DOI: 10.1016/j.jconrel.2010.06.003.
Antibacterial activity and cytotoxicity of PEGylated poly(amidoamine) dendrimersw. Analette I. Lopez, Rose Y. Reins, Alison M. McDermott, Barbara W. Trautner and Chengzhi Cai. Molecular BioSystems. 2009, 10 (5), pp 1148-1156. May 28, 2009. DOI: 10.1039/b904746h.
Silica-Shelled Single Quantum Dot Micelles as Imaging Probes with Dual or Multimodality. Rumiana Bakalova, Zhivko Zhelev, Ichio Aoki, Hideki Ohba, Yusuke Imai, and Iwao Kanno. Anal. Chem. 2006, 78 (16) pp 5925–5932. July 14, 2006. DOI: 10.1021/ac060412b.
Development of Polyethylene Glycol-Conjugated Alendronate, a Novel Nitrogen-Containing Bisphosphonate Derivative: Evaluation of Absorption, Safety, and Effects After Intrapulmonary Administration in Rats. HIDEMASA KATSUMI, MIKI TAKASHIMA, JUN-ICHI SANO, KAZUSHI NISHIYAMA, NORIKO KITAMURA, TOSHIYASU SAKANE, TORU HIBI, AKIRA YAMAMOTO. Journal of Pharmaceutical Sciences. 2011, 100 (9) pp 3783-3792. May 12, 2011. DOI: 10.1002/jps.22620.
Novel Comb-Shaped PEGModification Enhances the Osteoclastic Inhibitory Effect and Bone Delivery of Osteoprotegerin After Intravenous Administration in Ovariectomized Rats. Yoshihiro Miyaji, Yuji Kasuya, Yoshitake Furuta, Atsushi Kurihara, Masayuki Takahashi, Ken-ichi Ogawara, Takashi Izumi & Osamu Okazaki & Kazutaka Higaki. Pharmaceutical Research. 2012, 29 (11) pp 3143-3155. June 23, 2012. DOI 10.1007/s11095-012-0807-4.
Laser-Activated Gene Silencing via Gold Nanoshell-siRNA Conjugates,Gary B Braun, Alessia Pallaoro, Guohui Wi, Dimitris Missirlis, Joseph A. Zasadzinski, Matthew Tirrell, and Norbert O. Reich. ACS Nano. 2009, 3 (7), pp 2007–2015. June 15, 2009. DOI:10.1021/nn900469q.
Hairpin Structure of a Biarsenical- Tetracysteine Motif Determined by NMR Spectroscopy, Fatemeh Madani, Jesper Lind, Peter Damberg, Stephen R. Adams, Roger Y. Tsien, and Astrid O. Graslund. JACS. 2009, 131 (13), pp 4613–4615. March 12, 2009. DOI: 10.1021/ja809315x.
Potent D-peptide inhibitors of HIV-1 entry, Brett D. Welch, Andrew P. VanDemark, Annie Heroux, Christopher P. Hill, and Michael S. Kay. PNAS. 2007, 43 (104), pp 16828-16833. October 23, 2007. DOI: 10.1073/pnas.0708109104.
Improved pharmacokinetics and immunogenicity profile of organophosphorus hydrolase by chemical modification with polyethylene glycol. Boris N. Novikov, Janet K. Grimsley, Rory J. Kern, James R. Wild, Melinda E. Wales. Elsevier. 2010, 3 (146) pp 318-325. September 15, 2010. DOI: 10.1016/j.jconrel.2010.06.003.
Antibacterial activity and cytotoxicity of PEGylated poly(amidoamine) dendrimersw. Analette I. Lopez, Rose Y. Reins, Alison M. McDermott, Barbara W. Trautner and Chengzhi Cai. Molecular BioSystems. 2009, 10 (5), pp 1148-1156. May 28, 2009. DOI: 10.1039/b904746h.
Silica-Shelled Single Quantum Dot Micelles as Imaging Probes with Dual or Multimodality. Rumiana Bakalova, Zhivko Zhelev, Ichio Aoki, Hideki Ohba, Yusuke Imai, and Iwao Kanno. Anal. Chem. 2006, 78 (16) pp 5925–5932. July 14, 2006. DOI: 10.1021/ac060412b.
Development of Polyethylene Glycol-Conjugated Alendronate, a Novel Nitrogen-Containing Bisphosphonate Derivative: Evaluation of Absorption, Safety, and Effects After Intrapulmonary Administration in Rats. HIDEMASA KATSUMI, MIKI TAKASHIMA, JUN-ICHI SANO, KAZUSHI NISHIYAMA, NORIKO KITAMURA, TOSHIYASU SAKANE, TORU HIBI, AKIRA YAMAMOTO. Journal of Pharmaceutical Sciences. 2011, 100 (9) pp 3783-3792. May 12, 2011. DOI: 10.1002/jps.22620.
Novel Comb-Shaped PEGModification Enhances the Osteoclastic Inhibitory Effect and Bone Delivery of Osteoprotegerin After Intravenous Administration in Ovariectomized Rats. Yoshihiro Miyaji, Yuji Kasuya, Yoshitake Furuta, Atsushi Kurihara, Masayuki Takahashi, Ken-ichi Ogawara, Takashi Izumi & Osamu Okazaki & Kazutaka Higaki. Pharmaceutical Research. 2012, 29 (11) pp 3143-3155. June 23, 2012. DOI 10.1007/s11095-012-0807-4.
Additional Search Phrases:
Molecular Weight: 509.54; single compound
CAS: 756525-90-3
Purity: > 97%
Spacers: dPEG® Spacer is 26 atoms and 29.8 Å
Shipping: Ambient
References: Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.
Short polyethylene glycol chains densely bound to soft nanotube channels for inhibition of protein aggregation. N. Kameta, T. Matsuzawa, K. Yaoi, and M. Masuda. RSC Advances. 2016, 6 (43) pp 36744-36750. April 7, 2016. DOI: 10.1039/C6RA06793J.
Laser-Activated Gene Silencing via Gold Nanoshell-siRNA Conjugates,Gary B Braun, Alessia Pallaoro, Guohui Wi, Dimitris Missirlis, Joseph A. Zasadzinski, Matthew Tirrell, and Norbert O. Reich. ACS Nano. 2009, 3 (7), pp 2007–2015. June 15, 2009. DOI:10.1021/nn900469q.
Hairpin Structure of a Biarsenical- Tetracysteine Motif Determined by NMR Spectroscopy, Fatemeh Madani, Jesper Lind, Peter Damberg, Stephen R. Adams, Roger Y. Tsien, and Astrid O. Graslund. JACS. 2009, 131 (13), pp 4613–4615. March 12, 2009. DOI: 10.1021/ja809315x.
Potent D-peptide inhibitors of HIV-1 entry, Brett D. Welch, Andrew P. VanDemark, Annie Heroux, Christopher P. Hill, and Michael S. Kay. PNAS. 2007, 43 (104), pp 16828-16833. October 23, 2007. DOI: 10.1073/pnas.0708109104.
Improved pharmacokinetics and immunogenicity profile of organophosphorus hydrolase by chemical modification with polyethylene glycol. Boris N. Novikov, Janet K. Grimsley, Rory J. Kern, James R. Wild, Melinda E. Wales. Elsevier. 2010, 3 (146) pp 318-325. September 15, 2010. DOI: 10.1016/j.jconrel.2010.06.003.
Antibacterial activity and cytotoxicity of PEGylated poly(amidoamine) dendrimersw. Analette I. Lopez, Rose Y. Reins, Alison M. McDermott, Barbara W. Trautner and Chengzhi Cai. Molecular BioSystems. 2009, 10 (5), pp 1148-1156. May 28, 2009. DOI: 10.1039/b904746h.
Silica-Shelled Single Quantum Dot Micelles as Imaging Probes with Dual or Multimodality. Rumiana Bakalova, Zhivko Zhelev, Ichio Aoki, Hideki Ohba, Yusuke Imai, and Iwao Kanno. Anal. Chem. 2006, 78 (16) pp 5925–5932. July 14, 2006. DOI: 10.1021/ac060412b.
Development of Polyethylene Glycol-Conjugated Alendronate, a Novel Nitrogen-Containing Bisphosphonate Derivative: Evaluation of Absorption, Safety, and Effects After Intrapulmonary Administration in Rats. HIDEMASA KATSUMI, MIKI TAKASHIMA, JUN-ICHI SANO, KAZUSHI NISHIYAMA, NORIKO KITAMURA, TOSHIYASU SAKANE, TORU HIBI, AKIRA YAMAMOTO. Journal of Pharmaceutical Sciences. 2011, 100 (9) pp 3783-3792. May 12, 2011. DOI: 10.1002/jps.22620.
Novel Comb-Shaped PEGModification Enhances the Osteoclastic Inhibitory Effect and Bone Delivery of Osteoprotegerin After Intravenous Administration in Ovariectomized Rats. Yoshihiro Miyaji, Yuji Kasuya, Yoshitake Furuta, Atsushi Kurihara, Masayuki Takahashi, Ken-ichi Ogawara, Takashi Izumi & Osamu Okazaki & Kazutaka Higaki. Pharmaceutical Research. 2012, 29 (11) pp 3143-3155. June 23, 2012. DOI 10.1007/s11095-012-0807-4.
Laser-Activated Gene Silencing via Gold Nanoshell-siRNA Conjugates,Gary B Braun, Alessia Pallaoro, Guohui Wi, Dimitris Missirlis, Joseph A. Zasadzinski, Matthew Tirrell, and Norbert O. Reich. ACS Nano. 2009, 3 (7), pp 2007–2015. June 15, 2009. DOI:10.1021/nn900469q.
Hairpin Structure of a Biarsenical- Tetracysteine Motif Determined by NMR Spectroscopy, Fatemeh Madani, Jesper Lind, Peter Damberg, Stephen R. Adams, Roger Y. Tsien, and Astrid O. Graslund. JACS. 2009, 131 (13), pp 4613–4615. March 12, 2009. DOI: 10.1021/ja809315x.
Potent D-peptide inhibitors of HIV-1 entry, Brett D. Welch, Andrew P. VanDemark, Annie Heroux, Christopher P. Hill, and Michael S. Kay. PNAS. 2007, 43 (104), pp 16828-16833. October 23, 2007. DOI: 10.1073/pnas.0708109104.
Improved pharmacokinetics and immunogenicity profile of organophosphorus hydrolase by chemical modification with polyethylene glycol. Boris N. Novikov, Janet K. Grimsley, Rory J. Kern, James R. Wild, Melinda E. Wales. Elsevier. 2010, 3 (146) pp 318-325. September 15, 2010. DOI: 10.1016/j.jconrel.2010.06.003.
Antibacterial activity and cytotoxicity of PEGylated poly(amidoamine) dendrimersw. Analette I. Lopez, Rose Y. Reins, Alison M. McDermott, Barbara W. Trautner and Chengzhi Cai. Molecular BioSystems. 2009, 10 (5), pp 1148-1156. May 28, 2009. DOI: 10.1039/b904746h.
Silica-Shelled Single Quantum Dot Micelles as Imaging Probes with Dual or Multimodality. Rumiana Bakalova, Zhivko Zhelev, Ichio Aoki, Hideki Ohba, Yusuke Imai, and Iwao Kanno. Anal. Chem. 2006, 78 (16) pp 5925–5932. July 14, 2006. DOI: 10.1021/ac060412b.
Development of Polyethylene Glycol-Conjugated Alendronate, a Novel Nitrogen-Containing Bisphosphonate Derivative: Evaluation of Absorption, Safety, and Effects After Intrapulmonary Administration in Rats. HIDEMASA KATSUMI, MIKI TAKASHIMA, JUN-ICHI SANO, KAZUSHI NISHIYAMA, NORIKO KITAMURA, TOSHIYASU SAKANE, TORU HIBI, AKIRA YAMAMOTO. Journal of Pharmaceutical Sciences. 2011, 100 (9) pp 3783-3792. May 12, 2011. DOI: 10.1002/jps.22620.
Novel Comb-Shaped PEGModification Enhances the Osteoclastic Inhibitory Effect and Bone Delivery of Osteoprotegerin After Intravenous Administration in Ovariectomized Rats. Yoshihiro Miyaji, Yuji Kasuya, Yoshitake Furuta, Atsushi Kurihara, Masayuki Takahashi, Ken-ichi Ogawara, Takashi Izumi & Osamu Okazaki & Kazutaka Higaki. Pharmaceutical Research. 2012, 29 (11) pp 3143-3155. June 23, 2012. DOI 10.1007/s11095-012-0807-4.
Additional Search Phrases:
m-dPEG8-NHS ester, PEG, dPEG, discrete PEG, polyethylene glycol, poly (ethylene glycol), Quanta, Quanta BioDesign, PEGylation reagent, m-PEG, mPEG, mPEG NHS, m-PEG NHS, N-hydroxysuccinimide, NHS, NHS ester, mPEG NHS ester, active ester, mPEG active ester, mPEG with active ester, amine reactive, amino reactive, amine, amino, chemical modification, chemical modification reagent, PEG8, mPEG8, m-PEG8, methoxy-PEG, m-PEG8-NHS ester, mPEG8-NHS ester, Methyl-PEG8-NHS ester, MS(PEG)8, mPEG-NHS ester
SDS Datasheet
Concentration:
Format:
Buffer:
Preservative:
Storage:
Target Antigen:
Host:
Clonality:
Minimal Cross Reactivity To:
Country of Origin:
Label:
Ratio:
Excitation / Emission Maximum:
A280 Correction Factor:
Sensitivity:
Reactive Group:
Extinction Coefficient:
Spectrally Similar Dyes:
Molecular Weight:
Product Type:
pH:
Packaging:
Concentration:
Format:
Buffer:
Preservative:
Storage:
Target Antigen:
Host:
Clonality:
Minimal Cross Reactivity To:
Country of Origin:
Label:
Ratio:
Excitation / Emission Maximum:
A280 Correction Factor:
Sensitivity:
Reactive Group:
Extinction Coefficient:
Spectrally Similar Dyes:
Molecular Weight:
Product Type:
pH:
Packaging:
m-dPEG®₈-NHS ester
$175.00 – $500.00
m-dPEG®8-NHS ester, product number 10260, is a medium length, methyl-terminated, discrete length polyethylene glycol (dPEG®) spacer. With a reactive end as the N-hydroxysuccinimidyl (NHS) ester, m-dPEG®8-NHS ester is designed to modify surfaces containing accessible free amines. NHS reacts optimally with free amines at pH 7.2 – 7.5. The hydrolytic rate of the ester to the carboxylic acid increases with increasing pH. Please note that modification of surface amines on biomolecules (e.g., proteins and peptides) with this uncharged, methyl-capped dPEG® spacer may alter the overall charge of the resulting conjugates.
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