SDSMolecular Weight: 685.75; single compound
CAS: 756525-94-7
Purity: > 98%
Spacers: dPEG® Spacer is 38 atoms and 44.7 Å
Shipping: Ambient
References: Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.
The impact of molecular Weight and PEG Chain Length on the Systemic Pharmacokinetics of PEGylated Poly L-Lysine Dendrimers. Lisa M. Kaminskas, Ben J. Boyd, Peter Karellas, Guy Y. Krippner, Romina Lessene, Brian Kelly, and Christopher J. H. Porter. Molecular Pharmaceutics. 2008, 5 (3), pp 449–463. April 5, 2008. DOI: 10.1021/mp7001208.
Pharmacokinetics and Tumor Disposition of PEGylated Methotrexate Conjugated Poly-L-lysine Dendrimers. Lisa M. Kaminskas, Brian D. Kelly, Victoria M. McLeod, Ben J. Boyd, Guy Y. Krippner, Elizabeth D. Williams, and Christopher J. H. Porter, Molecular Pharmaceutics, Vol. 6, No. 4, 2009, 6 (4), pp 1190-1204, May 19, 2009. DOI: 10.1021/mp900049a.
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Stability, Antimicrobial Activity, and Cytotoxicity of Poly(amidoamine) Dendrimers on Titanium Substrates. Lin Wang, Uriel J. Erasquin, Meirong Zhao, Li Ren, Martin Yi Zhang, Gary J. Cheng, Yingjun Wang, and Chengzhi Cai. ACS Applied Materials & Interfaces. 2011, 3 (8), pp 2885-2894. July 20, 2011. DOI: 10.1021/am2004398.
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Development and Application of a Multimodal Contrast Agent for SPECT/CT Hybrid Imaging. Jason M. Criscione, Lawrence W. Dobrucki, Zhen W. Zhuang, Xenophon Papademetris, Michael Simons, Albert J. Sinusas and Tarek M. Fahmy. Bioconjugate Chemistry. 2011, 22 (9), pp 1784–1792. August 18, 2011. DOI: 10.1021/bc200162r.
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Acid-degradable cationic methacrylamide polymerized in the presence of plasmid DNA as tunable non-viral gene carrier. In Kap Ko, Assem Ziady, Shiwei Lu, Young Jik Kwon. Biomaterials. 2008, 29 (28) pp 3872–3881. June 27, 2008. DOI: 10.1016/j.biomaterials.2008.06.003.
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Poly(ethylene oxide)-bonded stationary phase for capillary ion chromatography. Toyohide Takeuchi, Budhi Oktavia, Lee Wah Lim. Anal Bioanal Chem. 2009, 393(4) pp 1267-1272. November 30, 2008. DOI: 10.1007/s00216-008-2533-7.
An adsorption chromatography assay to probe bulk particle transport through hydrogels. I. Vladescu, O. Lieleg, S. Jang, and Katharina Ribbeck. Journal of Pharmaceutical Sciences. 2012, 101 (1) pp 436-442. September 8, 2011. DOI: 10.1002/jps.2273.
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Stabilization of α-chymotrypsin upon PEGylation correlates with reduced structural dynamics. Jose A. Rodriguez-Martinez, Ricardo J. Sola, Betzaida Castillo, Hector R. Cintron-Colon, Izarys Rivera-Rivera, Gabriel Barletta, Kai Griebenow. Biotechnology and Bioengineering. 2008, 101 (6) pp 1142-1149. December 15, 2008. DOI: 10.1002/bit.22014.
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Characterization of Particle Translocation through Mucin Hydrogels. Oliver Lieleg, Ioana Vladescu, and Katharina Ribbeck. Biophysical Journal. 2010, 98 (9) pp 1782–1789. May 5, 2010. DOI: 10.1016/j.bpj.2010.01.012.
Short polyethylene glycol chains densely bound to soft nanotube channels for inhibition of protein aggregation. N. Kameta, T. Matsuzawa, K. Yaoi, and M. Masuda. RSC Advances. 2016, 6 (43) pp 36744-36750. April 7, 2016. DOI: 10.1039/C6RA06793J.
Site directed Pegylation: Role of pH and temperature, to increase the productivity of insulin oligomer conjugate. Ashutosh Sudhir Naik, Koduru srivatsa, Krishnappa Mane, Phanichand Kodali, Laxmi Adhikary. Journal of Pharmaceutical and Biological Sciences. 2017, 5(4) pp 155-160. 2017. https://innovativepublication.com/admin/uploaded_files/JPBS_5(4)_155-160.pdf
Protease-triggered siRNA delivery vehicles. David B. Rozema, Andrei V. Blokhin, Darren H. Wakefield, Jonathan D. Benson, Jeffrey C. Carlson, Jason J. Klein, Lauren J. Almeida, Anthony L. Nicholas, Holly L. Hamilton, Qili Chu, Julia O. Hegge, So C. Wong, Vladimir S. Trubetskoy, Collin M. Hagen, Eric Kitas, Jon A. Wolff, and David L. Lewis. Journal of Controlled Release. 2017, 209 pp 57-66. 7/10/2015. DOI: 10.1016/j.jconrel.2015.04.012.
Multivalent Benzamidine Molecules for Plasmin Inhibition: Effect of Valency and Linker Length. Tanmaye Nallan Chakravarthula, Dr. Ziqian Zeng, Prof. Nathan J. Alves. ChemMedChem, Volume 17, Issue 22, (2022), 09/16/2022, https://doi.org/10.1002/cmdc.202200364.
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