NHS-dPEG®₄-(m-dPEG®₁₂)₃-ester

TFP_Esters_Art2

SDS
Product #: 10401
NHS-dPEG®₄-(m-dPEG®₁₂)₃-ester
MW:    2420.80; single compound
dPEG® Spacer is 66 atoms and 52.7 Å, avg.
CAS #:    1334178-03-8

Size: 100 mg $250.00
Size: 1000 mg $1,300.00
Please call or email for bulk pricing and custom syntheses!
Products Protected under U.S. Patents # 7,888,536 & 8,637,711

 

References:

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Towards the Development of Hemerythrin-Based Blood Substitutes. Augustin C. Mot, Alina Roman, Iulia Lupan , Donald M. Kurtz Jr , Radu Silaghi-Dumitrescu. Protein J. 2010, 29 (6) pp 87-393. June 27, 2010. DOI: 10.1007/s10930-010-9264-2.

Rapid Raman Imaging of Stable, Functionalized Nanoshells in Mammalian Cell Cultures. Yiming Huang, Vimal P. Swarup, Sandra Whaley Bishnoi. Nano Letters. 2009, 9 (8) pp 2914-2920. May 23, 2009. DOI: 10.1021/nl901234x.

Differential patterning of neuronal, glial and neural progenitor cells on phosphorus-doped and UV irradiated diamond-like carbon. Edward M. Regan, James B. Uney, Andrew D. Dick, Yiwei Zhang, Jose Nunez-Yanez, Joseph P. McGeehan, Frederik Claeyssens, Stephen Kelly. Biomaterials. 2010, 31 (2) pp 207-215. October 14, 2009. DOI: 10.1016/j.biomaterials.2009.09.042.

Different radiolabelling methods alter the pharmacokinetic and biodistribution properties of Plasminogen Activator Inhibitor Type 2 (PAI-2) forms. Marie Ranson, Paula Berghofer, Kara L. Vine, Ivan Greguric, Rachael Shepherd, Andrew Katsifis. Nuclear Medicine and Biology. 2012, 39 (6) pp 833-839. January 17, 2012. DOI: 10.1016/j.nucmedbio.2012.01.006.

Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy. Zhuang Liu, Corrine Davis, Weibo Cai, Lina He, Xiaoyuan Chen, and Hongjie Dai. PNAS. 2008, 105 (5) pp 1410-1415. February 5, 2008. DOI: 10.1073_pnas.0707654105.

Synthesis and Preliminary Biological Evaluation of High-Drug-Load Paclitaxel-Antibody Conjugates for Tumor-Targeted Chemotherapy. Sherly Quiles, Kevin P. Raisch, Leisa L. Sanford, James A. Bonner, and Ahmad Safavy. Journal of Medicinal Chemistry. 2009, 53 (2) pp 586-594. December 3, 2009. DOI: 10.1021/jm900899g.

TIRF microscopy as a screening method for non-specific binding on surfaces. Christy Charlton, Vladimir Gubala, Ram Prasad Gandhiraman, Julie Wiechecki, Nam Cao Hoai Le, Conor Coyle, Stephen Daniels, Brian D. MacCraith, David E. Williams. Journal of Colloid and Interface Science. 2011, 354 (1) pp 405-409. February 1, 2011. DOI: 10.1016/j.jcis.2010.10.029.

Influence of PEGylation with linear and branched PEG chains on the adsorption of glucagon to hydrophobic surfaces. Charlotte Pinholt , Jens Thostrup Bukrinsky, Susanne Hostrup, Sven Frokjaer, Willem Norde, Lene Jorgensen. European Journal of Pharmaceutics and Biopharmaceutics. 2010, 77 (1) pp 139–147. November 3, 2010. DOI: 10.1016/j.ejpb.2010.11.001.

The influence of polyethylence glycol structure on the conjugation of recombinant human interferon a2b overproduced using synthetic gene in E. coli. Heni Rachmawati, Prima L. Febrina, Ratih A, Ningrum, Debbie S. Retnoningrum. International Journal of Research in Pharmaceutical Sciences. 2012, 3(2) pp 228-233. March 20, 2012. ISSN: 0975-7538.

Monitoring Protein PEGylation with Ion Exchange Chromatography. Peter Yu, Deanna Hurum, Leo Wang, Terry Zhang,and Jeffrey Rohrer. ThermoFisher Scientific Poster Note. 2013, PN70510_E01/3s.

New Assay for Quantification of PEGylated Proteins During in Vitro Permeability Studies. Spela Jalen, Vanja Smilovic, Katarina Fidler, Barbara Podobnik, Maja Marusic, Radovan Komel, Vladka Gaberc-Porekar and Simona Jevsevar. Acta Chimica Slovenica. 2014, 61 (3) pp 615-622. January 15, 2014.

Nanometer size silicon particles for hyperpolarized MRI. Grzegorz Kwiatkowski, Fabian Jahnig, Jonas Steinhauser, Patrick Wespi, Matthias Ernst, and Sebastian Kozerke. Scientific Reports. 2017, 7 (7946) pp 1-9. August 11, 2017. DOI: 10.1038/s41598-017-08709-0.

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  • TFP-dPEG®₄-(m-dPEG®₁₁)₃-ester
    MW:    2339.63; single compound
    dPEG® Spacer is 63 atoms and 49.200 Å, avg.
    CAS #:    N/A

References:

TFP-dPEG®₄-(m-dPEG®₁₁)₃-ester (#11401)
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Synthesis and Preliminary Biological Evaluation of High-Drug-Load Paclitaxel-Antibody Conjugates for Tumor-Targeted Chemotherapy, Sherly Quiles, Kevin P. Raisch, Leisa L. Sanford, James A. Bonner, and Ahmad Safavy, J Med. Chem., 2010, 53 (2), pp 586-594, December 3, 2009. DOI: 10.1021/jm900899g.

Visualizing Systemic Clearance and Cellular Level Biodistribution of Gold Nanorods by Intrinsic Two-Photon Luminescence, Ling Tong, Wei He, Yanshu Zhang, Wei Zheng, and Ji-Xin Cheng, Langmuir 2009, 25 (21), pp 12454-12459. DOI: 10.1021/la902992w.

A New Polyethyleneglycol-Derivatized Hemoglobin Derivative with Decreased Oxygen Affinity and Limited Toxicity. Oana Zolog, Augustin Mot, Florina Deac, Alina Roman, Eva Fischer-Fodor, Radu Silaghi-Dumitrescu. The Protein Journal. 2010 1 (30), pp 27-31. December 16, 2012 DOI: 10.1007/s10930-010-9298-5.

Improved pharmacokinetics and immunogenicity profile of organophosphorus hydrolase by chemical modification with polyethylene glycol. Boris N. Novikov, Janet K. Grimsley, Rory J. Kern, James R. Wild, Melinda E. Wales. Elsevier. 2010 146 (3) Pages 318-325 September 15, 2010. DOI: 10.1016/j.jconrel.2010.06.003.