Specs:

 SDS

Molecular Weight: 224.32; single compound

CAS: 52190-55-3

Spacers: dPEG® Spacer is 14 atoms and 15.8 Å

References: Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Gold nanoparticle-based fluorescence quenching via metal coordination for assaying protease activity. Se Yeon Park, So Min Lee, Gae Baik, Kim and Young-Pil Kim. Gold Bull. 2012, 45 pp 213–219. October 25, 2012. DOI: 10.1007/s13404-012-0070-9.

Polymerase Chain Reaction-Free Variable-Number Tandem Repeat Typing Using Gold Nanoparticle–DNA Monoconjugates. Jong Young Choi , Yong Tae Kim , and Tae Seok Seo. ACS Nano 2013, 7 (3) pp 2627–2633. February 12, 2013. DOI: 10.1021/nn400004d.

Near-Infrared-Activated Fluorescence Resonance Energy Transfer-Based Nanocomposite to Sense MMP2-Overexpressing Oral Cancer Cells. Yung-Chieh Chan, Ming-Hsien Chan, Chieh-Wei Chen, Ru-Shi Liu, Michael Hsiao, and Din Ping Tsai. ACS Omega. 2018,3 (2) pp. 1627-1634. February 8, 2018. DOI: 10.1021/acsomega.7b01494.




Additional Search Phrases: m-dPEG4-Thiol, 52190553, PEG, dPEG, discrete PEG, polyethylene glycol, poly (ethylene glycol), Quanta, Quanta BioDesign, PEGylation reagent, mPEG, m-PEG, methoxy PEG, mPEG-thiol, mPEG thiol, mPEG4, PEG4, metal surface modification reagent, surface modification reagent, surface modification, gold surface, gold surface, gold nanoparticle, chemical modification, chemical modification reagent

m-dPEG®₄-Thiol

$150.00 – $355.00

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Product#: 10792 Categories: , ,

m-dPEG®4-thiol, product number 10792, is a monodisperse PEGylation reagent designed to modify gold and silver surfaces or biomolecules that contain free, surface-accessible thiols. The single molecular weight, discrete-length PEG (dPEG®) spacer is 14 atoms (15.8 Å) long. One end of the spacer terminates with a methyl group, while the other end terminates with a sulfhydryl. The sulfhydryl group forms dative bonds with gold and disulfides with free thiols under non-reducing conditions.

This product is useful for the passivation of gold surfaces. The hydrophilic, non-immunogenic dPEG® spacer eliminates non-specific interactions with the gold surface.

If reacted with free thiols on biomolecules, m-dPEG®4-thiol forms disulfide bonds. Moreover, the resulting conjugates display improved water solubility and increased hydrodynamic volume. Furthermore, conjugation of this product with biomolecules potentially reduces or eliminates non-specific interactions and immunogenicity.

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What is dPEG®?

Frequently Asked Questions (about dPEG® products)

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Additional information

Weight.5 oz
Dimensions.75 × .75 × 2 in

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