Specs:

 SDS

Molecular Weight: 224.32; single compound

CAS: 52190-55-3

Purity: > 98%

Spacers: dPEG® Spacer is 14 atoms and 15.8 Å

Shipping: Ambient

References: Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Gold nanoparticle-based fluorescence quenching via metal coordination for assaying protease activity. Se Yeon Park, So Min Lee, Gae Baik, Kim and Young-Pil Kim. Gold Bull. 2012, 45 pp 213–219. October 25, 2012. DOI: 10.1007/s13404-012-0070-9.

Polymerase Chain Reaction-Free Variable-Number Tandem Repeat Typing Using Gold Nanoparticle–DNA Monoconjugates. Jong Young Choi , Yong Tae Kim , and Tae Seok Seo. ACS Nano 2013, 7 (3) pp 2627–2633. February 12, 2013. DOI: 10.1021/nn400004d.

Near-Infrared-Activated Fluorescence Resonance Energy Transfer-Based Nanocomposite to Sense MMP2-Overexpressing Oral Cancer Cells. Yung-Chieh Chan, Ming-Hsien Chan, Chieh-Wei Chen, Ru-Shi Liu, Michael Hsiao, and Din Ping Tsai. ACS Omega. 2018,3 (2) pp. 1627-1634. February 8, 2018. DOI: 10.1021/acsomega.7b01494.

Magnetic Nanoparticle Tracking for One-Step Protein Seperation and Binding Kinetics Analysis. Yunlei Zhao, Guangzhong Ma, Shaopeng Wang. Journal of The Electrochemical Society. 2022. May 11, 2022. dx.doi.org/10.1149/1945-7111/ac6bc5.

NEW FRONTIERS FOR TRIPLE NEGATIVE BREAST CANCER DETECTION AND TREATMENT: FROM MECHANICAL BIOMARKERS TO SPECIFIC NANOPARTICLE ENTRY FOR ROBOTICALLY CONTROLLED LASER-INDUCED HYPERTHERMIA. Vanessa Uzonwanne. Worchester Polytechnic Institute. 2022. May 22, 2022.

Charge-Sensitive Optical Detection of Binding Kinetics between Phage-Displayed Peptide Ligands and Protein Targets. Runli Liang, Yingnan Zhang, Guangzhong Ma, Shaopeng Wang. MDPI. 2022. Biosensors 2022, 12(6), 394. June 8, 2022. https://doi.org/10.3390/bios12060394

Label-Free Single-Molecule Pulldown for the Detection of Released Cellular Protein Complexes. Guangzhong Ma, Pengfei Zhang, Xinyu Zhou, Zijian Wan, and Shaopeng Wang. ACS Cent. Sci. 2022, 8, 9, 1272–1281. 2022. https://doi.org/10.1021/acscentsci.2c00602

Additional Search Phrases:

m-dPEG4-Thiol, 52190553, PEG, dPEG, discrete PEG, polyethylene glycol, poly (ethylene glycol), Quanta, Quanta BioDesign, PEGylation reagent, mPEG, m-PEG, methoxy PEG, mPEG-thiol, mPEG thiol, mPEG4, PEG4, metal surface modification reagent, surface modification reagent, surface modification, gold surface, gold surface, gold nanoparticle, chemical modification, chemical modification reagent, m-PEG4-thiol, mPEG4-SH, mPEG-thiol



 SDS    Datasheet

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m-dPEG®₄-Thiol

$150.00 – $355.00

Clear
PRODUCT IS SOLD STRICTLY FOR INTERNAL LABORATORY AND RESEARCH PURPOSES ONLY AND HAS NOT BEEN REVIEWED BY THE FDA. PRODUCT IS NOT FOR RESALE AND CANNOT BE INCORPORATED INTO COMMERCIAL GOODS FOR ANY USE OR USED IN THE DEVELOPMENT OF COMMERCIAL PRODUCTS OR IN THE PERFORMANCE OF COMMERCIAL SERVICES UNLESS UNDER A SEPARATE LICENSING, SUPPLY, OR DISTRIBUTOR AGREEMENT WITH QUANTA BIODESIGN, LTD. For information pertaining to the commercial use of our products, please click here to contact us.

Email Sales@QuantaBioDesign.com for Bulk Pricing and Custom Syntheses
Product#: 10792 Categories: ,

m-dPEG®4-thiol, product number 10792, is a monodisperse PEGylation reagent designed to modify gold and silver surfaces or biomolecules that contain free, surface-accessible thiols. One end of the spacer terminates with a methyl group, while the other end terminates with a sulfhydryl. The sulfhydryl group forms dative bonds with gold and disulfides with free thiols under non-reducing conditions.

This product is useful for the passivation of gold surfaces. The hydrophilic, non-immunogenic dPEG® spacer eliminates non-specific interactions with the gold surface.

If reacted with free thiols on biomolecules, m-dPEG®4-thiol forms disulfide bonds. Moreover, the resulting conjugates display improved water solubility and increased hydrodynamic volume. Furthermore, conjugation of this product with biomolecules potentially reduces or eliminates non-specific interactions and immunogenicity.

Learn more about Quanta BioDesign’s dPEG® products!

What is dPEG®?

Frequently Asked Questions (about dPEG® products)

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Additional information

Weight .5 oz
Dimensions .75 × .75 × 2 in

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