Specs:

 SDS

Molecular Weight: 1768.07; single compound

CAS: 88504-24-9

Spacers: dPEG® Spacer is 116 atoms and 137.2 Å

Shipping: Ambient

References: Greg T. Hermanson, Bioconjugate Techniques, 2nd Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0). See all of the extensive references to the reactions of maleimides with a variety of compounds and applications, Hermanson, p.1174 (index for maleimides) and references therein.

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Additional Search Phrases: m-dPEG36-MAL, PEG, dPEG, discrete PEG, polyethylene glycol, poly (ethylene glycol), Quanta, Quanta BioDesign, PEGylation reagent, PEG36, m-PEG, mPEG, m-PEG-MAL, mPEG-MAL, mPEG-maleimide, m-PEG-maleimide, maleimide, maleimido, chemical modification, chemical modification reagent, thiol reactive, sulfhydryl reactive, maleimide thiol reaction, Michael reaction, Michael addition, PEG36, maleimide mPEG, MAL mPEG, maleimide-m-PEG, maleimido mPEG, methoxy-PEG, m-PEG36-MAL, mPEG36-maleimide, mPEG1500-maleimide, mPEG-maleimide

 SDS    Datasheet

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m-dPEG®₃₆-MAL

$350.00 – $1,400.00

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PRODUCT IS SOLD STRICTLY FOR INTERNAL LABORATORY AND RESEARCH PURPOSES ONLY AND HAS NOT BEEN REVIEWED BY THE FDA. PRODUCT IS NOT FOR RESALE AND CANNOT BE INCORPORATED INTO COMMERCIAL GOODS FOR ANY USE OR USED IN THE DEVELOPMENT OF COMMERCIAL PRODUCTS OR IN THE PERFORMANCE OF COMMERCIAL SERVICES UNLESS UNDER A SEPARATE LICENSING, SUPPLY, OR DISTRIBUTOR AGREEMENT WITH QUANTA BIODESIGN, LTD. For information pertaining to the commercial use of our products, please click here to contact us.

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Product#: 10931 Categories: , , Tags: , , , , , , , , , , , , ,

m-dPEG®36-MAL, product number 10931, is a methyl-terminated, thiol-reactive, monodispersed PEGylation product designed for surface and biomolecule modification. One end of the molecule terminates in a maleimido-propionic acid group, which conjugates to the dPEG® spacer by an amide bond. The maleimide moiety reacts with sulfhydryls to form a thioether bond.

PEGylation with dPEG® reagents

The dPEG® tradename is Quanta BioDesign’s internationally recognized name for monodispersed PEGylation reagents. Quanta BioDesign synthesizes all of its single molecular weight dPEG® products from high-purity starting materials. We build them in stepwise processes to form high-purity final products. Our dPEG® products are quite different from traditional PEGylation reagents, which are dispersed polymers. dPEG® compounds provide all of the benefits of conventional polymer PEGylation reagents, but they have no dispersity (Ð = 1), which means that conjugates formed with dPEG® products are simpler to analyze than products created with polymer PEG products. We build our products with a variety of architectures and a diverse set of functional, reactive, and protective groups to provide our customers as much help as possible to accomplish their goals.

Learn more!

What is dPEG®?

Frequently Asked Questions (about dPEG® products)

m-dPEG®36-MAL is one member in a line of products with different dPEG® spacer lengths. There are many possible uses for this product. These uses include the following:

  • Surface coating and passivation of thiolated nanoparticles;
  • Modification of cysteine residues on peptides, proteins, and other sulfhydryl-containing molecules to increase hydrophilicity and decrease immunogenicity;
  • Modification of cysteine residues on peptides, proteins, and other sulfhydryl-containing molecules to increase hydrodynamic volume and reduce or eliminate renal clearance of the modified compound;
  • Supramolecular construction (for example, of hydrogels); and,
  • As a probe of protein structure or enzymatic function.

Bulk quantities of m-dPEG®36-MAL are available

If you need bulk product in a larger package size than our standard sizes, please contact us for a quote. Our commercial capabilities permit us to manufacture this product at any scale that you need.

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Additional information

Weight .5 oz
Dimensions .75 × .75 × 2 in

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