Specs:

 SDS

Molecular Weight: 766.77; single compound

CAS: N/A

Purity: > 97%

Spacers: dPEG® Spacer is 40 atoms and 46.2 Å

Shipping: Ambient

References: Greg T. Hermanson, Bioconjugate Techniques, 2nd Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0). Specifically see pp. 726-729 in his Chapter 18 on discrete PEG compounds for pegylation applications.

Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full overview of the dPEG® products.

Additional Search Phrases:

PEG, dPEG, discrete PEG, polyethylene glycol, PEGylation reagent, Quanta, Quanta BioDesign, PEGylation reagent, Hydroxy-PEG12-TFP ester, HO-PEG12-TFP ester, PEG600-TFP ester, Hydroxy-PEG-TFP ester



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Hydroxy-dPEG®₁₂-TFP ester

$180.00 – $600.00

Clear
PRODUCT IS SOLD STRICTLY FOR INTERNAL LABORATORY AND RESEARCH PURPOSES ONLY AND HAS NOT BEEN REVIEWED BY THE FDA. PRODUCT IS NOT FOR RESALE AND CANNOT BE INCORPORATED INTO COMMERCIAL GOODS FOR ANY USE OR USED IN THE DEVELOPMENT OF COMMERCIAL PRODUCTS OR IN THE PERFORMANCE OF COMMERCIAL SERVICES UNLESS UNDER A SEPARATE LICENSING, SUPPLY, OR DISTRIBUTOR AGREEMENT WITH QUANTA BIODESIGN, LTD. For information pertaining to the commercial use of our products, please click here to contact us.

Email Sales@QuantaBioDesign.com for Bulk Pricing and Custom Syntheses
Product#: 11345 Categories: , , , , , Tags: ,

Hydroxy-dPEG®12-TFP ester, product number 11345, is a hydroxy-terminated, single molecular weight, discrete polyethylene glycol (dPEG®) compound that has a 2,3,5,6-tetrafluorophenyl (TFP) ester for conjugation to primary and secondary amines. TFP esters outperform traditional N-hydroxysuccinimide (NHS) esters because TFP esters are less susceptible to hydrolysis and more reactive towards primary and secondary amines than NHS esters. For more information on the superiority of TFP esters over NHS esters, please see, TFP Esters Have More Hydrolytic Stability and Greater Reactivity Than NHS Esters. Uses for this product include:

  • modification of amine-functionalized surfaces (g., silica, glass);
  • modification of proteins and peptides at accessible amine sites on the molecules; and,
  • construction of dendrimers, among many other applications.

To learn more about our dPEG® products, please click the links below:

What is dPEG®?

Frequently Asked Questions (about dPEG® products)

If you need a larger amount of our product that our standard package sizes, please contact us and request a quote. Our commercial capabilities allow us to manufacture PN11345 in any size lot you need.

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Application References:

  1. Hermanson, G. T. Chapter 2, Functional Targets for Bioconjugation. Bioconjugate Techniques, 3rd edition. Academic Press: New York, 2013, 127-228. Bioconjugate Techniques by Greg Hermanson is considered by most bioconjugation experts to be an indispensable reference in this field. We encourage all of our customers to purchase a copy, and we make it available on our website. Are you interested? If so, please click here to read a review of the book and to purchase it.
  2. Hermanson, G. T. Chapter 3, The Reactions of Bioconjugation. Bioconjugate Techniques, 3rd edition. Academic Press: New York, 2013, 229-258.
  3. Hermanson, G. T. Chapter 8, Dendrimers and Dendrons. Bioconjugate Techniques, 3rd edition. Academic Press: New York, 2013, 351-386.
  4. Hermanson, G. T. Chapter 18, PEGylation and Synthetic Polymer Modification. Bioconjugate Techniques, 3rd edition. Academic Press: New York, 2013, 787-838.

Additional information

Weight .5 oz
Dimensions .75 × .75 × 2 in

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