Additional information
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PEG, dPEG, discrete PEG, polyethylene glycol, PEGylation reagent, maleimide, maleimido, thiol reactive, sulfhydryl reactive, pharmacokinetic, pharmacokinetics, serum half-life, branched PEG, pharmacodynamic, pharmacodynamics, chemical modification reagent, chemical modification reagents, serum half-life modifier, carboxyl terminated, carboxylic acid terminated, carboxylic acid, carbonyl, MAL-PEG12-Tris(m-PEG24)3, MAL-NH-PEG600-Tris(mPEG1000)3, Branched mPEG-maleimide, Amino-PEG12-Tris(m-PEG24)3, H2N-PEG600-Tris(mPEG1000)3, Branched mPEG-amine
$250.00 – $750.00
MAL-dPEG®12-Tris(m-dPEG®24)3, product number 11471, is a thiol-reactive, methyl-terminated, four-arm monodispersed PEG product designed to modulate biodistribution of conjugates. Tris forms the core of the molecule. Three equal-length methyl-terminated long arms plus one maleimido-terminated short arm extend from the tris core. The amphiphilic PEG imparts hydrophilicity to conjugates, reduces or eliminates the conjugates’ antigenicity, and increases the hydrodynamic volume of conjugated molecules. Applications for this product include eradicating renal clearance, maintaining in vivo circulation for more extended periods, and suppressing immune responses to conjugates.