Azido-dPEG®x-NHS ester

Azido-dPEG®x-NHS ester
  • Azido-dPEG®₄-NHS ester
    MW:    388.37; single compound
    dPEG® Spacer is 16 atoms and 17.951 Å
    CAS #:    944251-24-5
  • Azido-dPEG®₈-NHS ester
    MW:    564.58; single compound
    dPEG® Spacer is 28 atoms and 32.127 Å
    CAS #:    1204834-00-3
  • Azido-dPEG®₁₂-NHS ester
    MW:    740.79; single compound
    dPEG® Spacer is 40 atoms and 46.306 Å
    CAS #:    1108750-59-9

References:

Azido-dPEG®₄-NHS ester (#10501)
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Chemoselective Immobilization of Peptides on Abiotic and Cell Surfaces at Controlled Densities. Venkata R. Krishnamurthy, John T. Wilson, Wanxing Cui, XueZheng Song, Yi Lasanajak, Richard D. Cummings, and Elliot L. Chaikof. Langmuir. 2010, 26 (11) pp 7675-7678. May 7, 2010. DOI: 10.1021/la101192v.

Constant-speed vibrational signaling along polyethylene glycol chain up to 60-Å distance. Zhiwei Lin and Igor V. Rubtsov. PNAS. 2012, 109 (5) pp 1413-1418. January 31, 2012. DOI:10.1073/pnas.1116289109.

Ballistic energy transport along PEG chains: distance dependence of the transport efficiency. Zhiwei Lin , Nan Zhang , Janarthanan Jayawickramarajah and Igor V. Rubtsov. Physical Chemistry Chemical Physics. 2012, 30 (14) pp 10445-10454. April 12, 2012. DOI: 10.1039/C2CP40187H.

An Intein-Mediated Site-Specific Click Conjugation Strategy for Improved Tumor Targeting of Nanoparticle Systems. Drew R. Elias, Dr. Zhiliang Cheng, and Prof. Andrew Tsourkas. Small. 2010, 6 (21) pp 2460–2468 November 5, 2010. DOI:10.1002/smll.201001095.

Peptide-Targeted Nanoglobular Gd-DOTA Monoamide Conjugates for Magnetic Resonance Cancer Molecular Imaging. Mingqian Tan, Xueming Wu, Eun-Kee Jeong, Qianjin Chen, and Zheng-Rong Lu. Biomacromolecules. 2010, 11 (3) pp 754–761. March 8, 2010. DOI:10.1021/bm901352v.

Protein addressing on patterned microchip by coupling chitosan electrodeposition and ‘electro-click’ chemistry. Xiao-Wen Shi,, Ling Qiu, Zhen Nie, Ling Xiao, Gregory F Payne and Yumin Du. Biofabrication. 2013, (5) 041001 pp 7. September 23, 2013. DOI:10.1088/1758-5082/5/4/041001.

Clickable Poly(ethylene glycol)-Microsphere-Based Cell Scaffolds. Peter K. Nguyen, Christopher G Snyder, Jason D. Shields, Amanda W. Smith, Donald L. Elbert. Macromolecular Journals. 2013, 214 (8) pp 948-956. March 4, 2013. DOI: 10.1002/macp.201300023.

Nano-Scale Alignment of Proteins on a Flexible DNA Backbone. Tatsuya Nojima1, Hiroki Konno, Noriyuki Kodera, Kohji Seio, Hideki Taguchi, Masasuke Yoshida. PLoS ONE. 2012, 7(12): e52534. December 26, 2012. DOI:10.1371/journal.pone.0052534.

A Mild and Reliable Method to Label Enveloped Virus with Quantum Dots by Copper-Free Click Chemistry. Jian Hao, Li-Li Huang, Rui Zhang, Han-Zhong Wang and Hai-Yan Xie. Analytical Chemistry. 2012, 84 (19) pp 8364−8370. September 4, 2012. DOI: org/10.1021/ac301918t.

ADIBO-Based ”Click” Chemistry for Diagnostic Peptide Micro-Array Fabrication: Physicochemical and Assay Characteristics. Denis Prim, Fabien Rebeaud, Vincent Cosandey, Roger Marti, Philippe Passeraub and Marc E. Pfeifer. ADIBO-Based ”Click” Chemistry for Diagnostic Peptide Micro-Array Fabrication: Physicochemical and Assay Characteristics. Denis Prim, Fabien Rebeaud, Vincent Cosandey, Roger Marti, Philippe Passeraub and Marc E. Pfeifer. Molecules. 2013, 18 pp 9833-9849. August 16, 2013. DOI: 10.3390/molecules18089833.

Bio-Inspired Liposomal Thrombomodulin Conjugate through Bio-Orthogonal Chemistry. Hailong Zhang, Jacob Weingart, Rui Jiang, Jianhao Peng, Qingyu Wu, and Xue-Long Sun. Bioconjugate Chemistry. 2013, 24 (4) pp 550–559. March 4, 2013. DOI: 10.1021/bc300399f.

Design and synthesis of glycoprotein-based multivalent glyco-ligands for influenza hemagglutinin and human galectin-3. Helen Wanga, Wei Huang, Jared Orwenyo, Aditi Banerjee, Gerardo R. Vasta, Lai-Xi Wang. Bioorganic & Medicinal Chemistry. 2013, 21 (7) pp 2037–2044. April 1, 2013. DOI: 10.1016/j.bmc.2013.01.028.

A Method for Determining Small Anharmonicity Values from 2DIR Spectra Using Thermally Induced Shifts of Frequencies of High-Frequency Modes. Zhiwei Lin , Patrick Keiffer , and Igor V. Rubtsov. Journal of Physical ChemistryB. 2011, 115 (18) pp 5347-5353. December 28, 2010. DOI: 10.1021/jp1094189.

3D Tumor tissue analogs and their orthotopic implants for understanding tumor-targeting of microenvironment-responsive nanosized chemotherapy and raditation. Pallavi Sethi, PhD., Amar Jyoti, PhD, Elden P. Swindell, PhD, Ryan Chan, PharmD, Ulrich W. Langner, DABR, PhD, Jonathan M. Feddock, MD, Radhakrishnan Nagarajan, PhD, Thomas V. O'Halloran, PhD, Meenakshi Upreti, PhD. Nanomedicine. 2015, 11 (8) pp 2013-2023. July 22,2015. DOI: 10.1016/j.nano.2015.07.013.

Click Chemistry Applied to the Synthesis of Salmonella Typhimurium O-Antigen Glycoconjugate Vaccine on Solid Phase with Sugar Recycling. Giuseppe Stefanetti, Allan Saul, Calman A. MacLennan and Francesca Micoli. Bioconjugate Chemistry. 2015. November 9, 2015. DOI: 10.1021/acs.bioconjchem.5b00521.

Energy Transport in PEG Oligomers: Contributions of Different Optical Bands. Layla N Qasim, Arkady A Kurnosov, Yuankai Yue, Zhiwei Lin, Alexander L Burin, and Igor V Rubtsov. The Journal of Physical Chemistry. 2016, October 31, 2016. DOI: 10.1021/acs.jpcc.6b09389.

Streptavidin-hydrogel prepared by sortase A-assisted click chemistry for enzyme immobilization on an electrode. Takuya Matsumoto, Yuki Isogawa, Tsutomu Tanaka, and Akihiko Kondo. Biosensors and Bioelectronics. 2017, 99 (2018) pp 56-61. July 17, 2017. DOI: http://dx.doi.org/10.1016/j.bios.2017.07.044.

Lysosomal Targeting Enhancement by Conjugation of Glycopeptides Containing Mannose-6-phosphate Glycans Derived from Glyco-engineered Yeast. Ji-Yeon Kang, Keun Koo Shin, Ha Hyung Kim, Jeong-Ki Min, Eun Sun Ji, Jin Young Kim, Ohsuk Kwon, & Doo-Byoung Oh. Scientific Reports. 2018, 8 (8730) pp 1-14. June 7, 2018. DOI: 10.1038/s41598-018-26913-4.

Streptavidin-hydrogel prepared by sortase A-assisted click chemistry for enzyme immobilization on an electrode. Takuya Matsumoto, Yuki Isogawa, Tsutomu Tanaka, and Akihiko Kondo. Biosensors and Bioelectronics. 2018, 99 pp 56-61. 1/15/2018. DOI: 10.1016/j.bios.2017.07.044.
Azido-dPEG®₈-NHS ester (#10503)
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

A Modular Platform for the Rapid Site-Specific Radiolabeling of Proteins with F Exemplified by Quantitative Positron Emission Tomography of Human Epidermal Growth Factor Receptor 2. Herman S. Gill, Jeff N. Tinianow, Annie Pgasawara, Judith E. Flores, Alexander N. Vanderbilt, Helga Raab, Justin M. Scheer, Richard Vandlen, Simon-P. Williams, and Jan Marik, J. Med. Chem., 2009, 52 (19), pp 5816–5825 September 9, 2009. DOI: 10.1021/jm900420c.

An Effective Targeted Nanoglobular Manganese(II) Chelate Conjugate for Magnetic Resonance Molecular Imaging of Tumor Extracellular Matrix. Mingqian Tan, Xueming Wu, Eun-Kee Jeong, Qianjin Chen, Dennis L. Parker, and Zheng-Rong Lu,Mol. Pharmaceutics, 2010, 7 (4), pp 936–943 May 19, 2010. DOI: 10.1021/mp100054m.

Constant-speed vibrational signaling along polyethylene glycol chain up to 60-Å distance. Zhiwei Lin and Igor V. Rubtsov. PNAS, 2012, 5 (109), pp 1413-1418, January 31, 2012. DOI:10.1073/pnas.1116289109.

Ballistic energy transport along PEG chains: distance dependence of the transport efficiency. Zhiwei Lin , Nan Zhang , Janarthanan Jayawickramarajah and Igor V. Rubtsov. Physical Chemistry Chemical Physics. 2012, 30 (14), pp 10445-10454. April 12, 2012. DOI: 10.1039/C2CP40187H.

Enzymatic Ligation of Large Biomolecules to DNA. Rasmus Schøler Sørensen, Anders Hauge Okholm, David Schaffert, Anne Louise Bank Kodal, Kurt V. Gothelf, and Jørgen Kjems. ACS Nano. 2013, 7 (9) pp 8098–8104. August 8, 2013. DOI: 10.1021/nn403386f.

Click Chemistry Immobilization of Antibodies on Polymer Coated Gold Nanoparticles. Chiara Finetti, Laura Sola, Margherita Pezzullo, Davide Prosperi, Miriam Colombo, Benedetta Riva, Svetlana Avvakumova, Carlo Morasso, Silvia Picciolini, and Marcella Chiari. Langmuir. 2016, 32, pp 7435-7441. July 1, 2016. DOI: 10.1021/acs.langmuir.6b01142.

Design, Synthesis, and Characterization of Fully Zwitterionic, Functionalized Dendrimers. Esther Roeven, Luc Scheres, Maarten M. J. Smulders, and Han Zuilhof. ACS Omega, 2019, 4 (2), pp 3000–3011. February 11, 2019. DOI: 10.1021/acsomega.8b03521.

Modular Assembly of Cell-targeting Devices Based on an Uncommon G-quadruplex Aptamer. Felipe Opazo, Laura Eiden, Line Hansen, Falk Rohrbach, Jesper Wengel, Jørgen Kjems, and Günter Mayer. Molecular Therapy Nucleic Acids. 2015, 4 pp e251. 9/1/2015. DOI: 10.1038/mtna.2015.25.
Azido-dPEG®₁₂-NHS ester (#10505)
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Chemoselective Immobilization of Peptides on Abiotic and Cell Surfaces at Controlled Densities. Venkata R. Krishnamurthy, John T. Wilson, Wanxing Cui, XueZheng Song, Yi Lasanajak, Richard D. Cummings, and Elliot L. Chaikof,Langmuir, 2010, 26 (11), pp 7675–7678, May 7, 2010. DOI: 10.1021/la101192v.

Constant-speed vibrational signaling along polyethylene glycol chain up to 60-Å distance. Zhiwei Lin and Igor V. Rubtsov. PNAS, 2012, 5 (109), pp 1413-1418, January 31, 2012. DOI: 10.1073/pnas.1116289109.

Ballistic energy transport along PEG chains: distance dependence of the transport efficiency. Zhiwei Lin , Nan Zhang , Janarthanan Jayawickramarajah and Igor V. Rubtsov. Physical Chemistry Chemical Physics. 2012, 30 (14), pp 10445-10454. April 12, 2012. DOI: 10.1039/C2CP40187H.

Shape-Encoded Chitosan-Polyacrylamide Hybrid Hydrogel Microparticles with Controlled Macroporous Structures via Replica Molding for Programmable Biomacromolecular Conjugation. Eunae Kang, Sukwon Jung, John H. Abel, Allison Pine, and Hyunmin Yi. Langmuir. 2016, 32 (21) pp 5394-5402. May 18, 2016. DOI: 10.1021/acs.langmuir.5b04653.

Towards personalized peptide-based cancer nanovaccines: a facile and versatile synthetic approach. Hamilton Kakwere, Elizabeth S Ingham, Riley Allen, Lisa M Mahakian, Sarah M Tam, Hua Zhang, Matthew Thomas Silvestrini, Jamal S Lewis, and Katherine W. Ferrara. Bioconjugate Chemistry. 2017, pp 1-27. September 28, 2017. DOI: 10.1021/acs.bioconjchem.7b00502.

Biomolecular Strategies for Cell Surface Engineering. John Tanner Wilson. Doctoral Dissertation, Georgia Institute of Technology: Atlanta, Georgia USA, 2009.