Fmoc-N-amido-dPEG®x-acid

Fmoc-N-amido-dPEG®x-acid
  • Fmoc-N-amido-dPEG®₂-acid
    MW:    399.44; single compound
    dPEG® Spacer is 10 atoms and 10.883 Å
    CAS #:    872679-70-4
  • Fmoc-N-amido-dPEG®₃-acid
    MW:    443.49; single compound
    dPEG® Spacer is 13 atoms and 14.408 Å
    CAS #:    867062-95-1
  • Fmoc-N-amido-dPEG®₄-acid
    MW:    487.54; single compound
    dPEG® Spacer is 16 atoms and 17.943 Å
    CAS #:    557756-85-1
  • Fmoc-N-amido-dPEG®₅-acid
    MW:    531.59; single compound
    dPEG® Spacer is 19 atoms and 21.493 Å
    CAS #:    882847-32-7
  • Fmoc-N-amido-dPEG®₆-acid
    MW:    575.65; single compound
    dPEG® Spacer is 22 atoms and 25.046 Å
    CAS #:    882847-34-9
  • Fmoc-N-amido-dPEG®₈-acid
    MW:    663.75; single compound
    dPEG® Spacer is 28 atoms and 32.122 Å
    CAS #:    756526-02-0
  • Fmoc-N-amido-dPEG®₁₂-acid
    MW:    839.96; single compound
    dPEG® Spacer is 40 atoms and 46.301 Å
    CAS #:    756526-01-9
  • Fmoc-N-amido-dPEG®₂₄-acid
    MW:    1368.59; single compound
    dPEG® Spacer is 76 atoms and 88.913 Å
    CAS #:    756526-01-9
  • Fmoc-N-amido-dPEG®₃₆-acid
    MW:    1897.22; single compound
    dPEG® Spacer is 112 atoms and 131.409 Å
    CAS #:    756526-01-9

References:

Fmoc-N-amido-dPEG®₂-acid (#10243)
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Functional PEG-Modified Thin Films for Biological Detection. Aaron S. Anderson, Andrew M. Dattelbaum, Gabriel A. Montano, Dominique N. Price, Jurgen G. Schmidt, Jennifer S. Martinez, W. Kevin Grace, Karen M. Grace, and Basil I. Swanson. Langmuir. 2008, 24 (5), pp 2240–2247. January 30, 2008. DOI: 10.1021/la7033438.

Polyproline-Rod Approach to Isolating Protein Targets of Bioactive Small Molecules: Isolation of a New Target of Indomethacin. Shin-ichi Sato, Youngjoo Kwon, Shinji Kamisuki, Neeta Srivastava, Quian Mao, Yoshinori Kawazoe, and Motonari Uesugi. J. Am. Chem. Soc. 2007, 129 (4), pp 873–880. January 4, 2007. DOI: 10.1021/ja0655643.

Oriented Surface Immobilization of Antibodies at the Conserved Nucleotide Binding Site for Enhanced Antigen Detection. Nathan J Alves, Tanyel Kiziltepe, and Basar Bilgicer. Langmuir. 2012, 28 (25) pp 9640-9648. May 21, 2012. DOI: 10.1021/la301887s.

Enhanced Cellular Uptake of Peptide-Targeted Nanoparticles through Increased Peptide Hydrophilicity and Optimized Ethylene Glycol Peptide-Linker Length. Jared F. Stefanick, Jonathan D. Ashley, and Basar Bilgicer. ACS Nano. 2013, 7 (9) pp 8115–8127. August 29, 2013. DOI: 10.1021/nn4033954.

Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site. Nathan J. Alves, Matthew M. Champion, Jared F. Stefanick, Michael W. Handlogten, Demetri T. Moustakas, Yunhua Shi, Bryan F. Shawd, Rudolph M. Navari, Tanyel Kiziltepe, Basar Bilgicer. Biomaterials. 2013, 34 (22) pp 5700–5710. April 16, 2013. DOI:.org/10.1016/j.biomaterials.2013.03.082.

Design, Synthesis and Evaluation of a Neurokinin 1 Receptor-Targeted Near IR Dye for Fluorescence Guided Surgery of Neuroendocrine Cancers. Ananda Kumar Kanduluru, Madduri Srinivasarao, and Philip S. Low. Bioconjugate Chemistry. 2016, pp 1-20. August 16, 2016. DOI: 10.1021/acs.bioconjchem.6b00374.

One-Pot Isolation of a Desired Human Genome Fragment by Using a Biotinylated pcPNA/S1 Nuclease Combination. Arivazhagan Rajendran , Narumi Shigi, Jun Sumaoka, and Makoto Komiyama. Biochemistry. 2018, 57, pp 2908-2912. May 3, 2018. DOI: 10.1021/acs.biochem.8b00202.

Stapled, Long-Acting Glucagon-like Peptide 2 Analog with Efficacy in Dextran Sodium Sulfate Induced Mouse Colitis Models. Peng-Yu Yang , Huafei Zou, Candy Lee, Avinash Muppidi, Elizabeth Chao, Qiangwei Fu, Xiaozhou Luo, Danling Wang, Peter G. Schultz, and Weijun Shen. Journal of Medicinial Chemistry. 2018, 61, pp 3218-3223. March 12, 2018. DOI: 10.1021/acs.jmedchem.7b00768.

Evaluation of the Pharmacokinetic Effects of Various Linking Group Using the 111In-DOTA-X-BBN(7−14)NH2 Structural Paradigm in a Prostate Cancer Model. Jered C. Garrison, Tammy L. Rold, Gary L. Sieckman, Farah Naz, Samantha V. Sublett, Said Daibes Figueroa, Wynn A. Volkert and Timothy J. Hoffman. Bioconjugate Chem. 2008, 19 (9) pp 1803–1812. August 20, 2008. DOI: 10.1021/bc8001375.

PEG-Peptide Conjugates. Ian W Hamley. Biomacromolecules. 2014. April 1, 2014. DOI: 10.1021/bm500246w.

Dual-receptor targeted strategy in nanoparticle design achieves tumor cell selectivity through cooperativity. Jared Francis Stefanick, David Thomas Omstead, Tanyel Kiziltepeabc and Basar Bilgicer. Nanoscale. 2019. Fenruary 17, 2019. DOI: 10.1039/C8NR09431D

Designer covalent heterobivalent inhibitors prevent IgE-dependent responses to peanut allergen. Peter E. Deak, Baksun Kim, Amina Abdul Qayum, Jaeho Shin, Girish Vitalpur, Kirsten M. Kloepfer, Matthew J. Turner, Neal Smith, Wayne G. Shreffler, Tanyel Kiziltepe, Mark H. Kaplan, and Basar Bilgicer. 2019. April 8, 2019. DOI: 10.1073/pnas.1820417116

Membrane-Fusogen Distance Is Critical for Efficient Coiled-Coil-Peptide-Mediated Liposome Fusion. Geert A. Daudey, Harshal R. Zope, Jens Voskuhl, Alexander Kros , and Aimee L. Boyle. Langmuir. 2017, 33 (43) pp 12443-12452. 10/5/2017. DOI: 10.1021/acs.langmuir.7b02931.

Design and Evaluation of Novel Polymyxin Fluorescent Probes. Bo Yun , Kade D. Roberts, Philip E. Thompson, Roger L. Nation, Tony Velkov, and Jian Li. Sensors. 2017, 17 (11) pp 2598. 11/11/2017. DOI: 10.3390/s17112598.
Fmoc-N-amido-dPEG®₃-acid (#10033)
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Trivalent PEGylated Platform for the Conjugation of Bioactive Compounds. Angela Torres, Carlos Mas-Moruno, Enrique Perez-Paya, Fernando Albericio, and Miriam Royo. Bioconjugate Chem. 2011, 22 (10), pp 2172–2178. August 25, 2011. DOI: 10.1021/bc100393g.

Development of Peptide Nucleic Acid Probes for Detection of the HER2 Oncogene. Belhu Metaferia., Jun S. Wei., Young K. Song, Jennifer Evangelista, Konrad Aschenbach, Peter Johansson, Xinyu Wen, Qingrong Chen, Albert Lee, Heidi Hempel, Jinesh S. Gheeya, Stephanie Getty, Romel Gomez, Javed Khan. PLoS ONE. 2012, 8 (4) e58870. April 10, 2013. DOI: 10.1371/journal.pone.0058870.

Enhanced Cellular Uptake of Peptide-Targeted Nanoparticles through Increased Peptide Hydrophilicity and Optimized Ethylene Glycol Peptide-Linker Length. Jared F. Stefanick, Jonathan D. Ashley, and Basar Bilgicer. ACS Nano. 2013, 7 (9) pp 8115–8127. August 29, 2013. DOI: 10.1021/nn4033954.

Quantifying Cellular Internalization with a Fluorescent Click Sensor. Laura I. Selby, Luigi Aurelio, Daniel Yuen, Bim Graham, and Angus P. R. Johnston. ACS Sensors. 2018, 3, pp 1182-1189. April 20, 2018. DOI: 10.1021/acssensors.8b00219.
Fmoc-N-amido-dPEG®₄-acid (#10213)
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Novel Synthetic Route to Peptide-Capped Gold Nanoparticles. Takeshi Serizawa, Yu Hirai, and Mamoru Aizawa. Langmuir. 2009, 25 (20), pp 12229–12234. September 21, 2009. DOI: 10.1021/la9021799.

Controlling HBV Replication in Vivo by Intravenous Administration of Triggered PEGylated siRNA-Nanoparticles. Sergio Carmona, Michael R. Jorgensen, Soumia Kolli, Carol Crowther, Felix H. Salazar, Patricia L. Marion, Masato Fujino, Yukikazu Natori, Maya Thanou, Patrick Arbuthnot, and Andrew D. Miller. Mol. Pharmaceutic., 2009, 6 (3), pp 706–717. January 21,2009. DOI: 10.1021/mp800157x.

Species Differences of Bombesin Analog Interactions with GRP-R Define the Choice of Animal Models in the Development of GRP-R-Targeting Drugs. Theodosia Maina, PhD; Berthold A. Nock, PhD; Hanwen Zhang, Anastasia Nikolopoulou, Msci, Beatrice Waser, PhD; Jean Claude Reubi, MD; and Helmut R. Maecke, PhD. Journal of Nuclear Medicine. 2005, 46 (5) pp. 823-830. January 23, 2005.

Polyproline-Rod Approach to Isolating Protein Targets of Bioactive Small Molecules: Isolation of a New Target of Indomethacin. Shin-ichi Sato, Youngjoo Kwon, Shinji Kamisuki, Neeta Srivastava, Quian Mao, Yoshinori Kawazoe, and Motonari Uesugi. J. Am. Chem. Soc. 2007, 129 (4), pp 873–880. January 4, 2007. DOI: 10.1021/ja0655643.

Photocleavable Peptide-Conjugated Magnetic Beads for Protein Kinase Assays by MALDI-TOF. MS. Guangchang Zhou, Xiaoliang Yan, Ding Wu, and Stephen J. Kron. Bioconjugate Chem. 2010, 21 (10), pp 1917–1924. September 22, 2010. DOI: 10.1021/bc1003058.

Neutrophil Targeting Heterobivalent SPECT Imaging Probe: cFLFLF-PEG-TKPPR-99mTc. Yi Zhang, Li Xiao, Mahendra D. Chordia, Landon W. Locke, Mark B. Williams, Stuart S. Berr, and Dongfeng Pan. Bioconjugate Chem. 2010, 21 (10), pp 1788–1793. September 15, 2010. DOI: 10.1021/bc100063a.

Evaluation of 99mTc-Labeled Cyclic RGD Peptide with a PEG4 Linker for Thrombosis Imaging: Comparison with DMP444. Wei Fang, Jia He, Young-Seung Kim, Yang Zhou, and Shuang Liu. Bioconjugate Chem. 2011, 22 (8), pp 1715–1722. July 24, 2011. DOI: 10.1021/bc2003742.

Expanding the Scope of Biocatalysis: Oxidative Biotransformations on Solid-Supported Substrates. Sarah J. Brooks, Lydie Coulombel, Disha Ahuja, Douglas S. Clark, and Jonathan S. Dordick. Advanced Synthesis & Catalysis. 2008, 350 (10), pp 1517–1525. July 7, 2008. DOI:10.1002/adsc.200800188.

Development of Peptide Nucleic Acid Probes for Detection of the HER2 Oncogene.

Belhu Metaferia., Jun S. Wei., Young K. Song, Jennifer Evangelista, Konrad Aschenbach, Peter Johansson, Xinyu Wen, Qingrong Chen, Albert Lee, Heidi Hempel, Jinesh S. Gheeya, Stephanie Getty, Romel Gomez, Javed Khan. PLoS ONE. 2012, 8 (4) e58870. April 10, 2013. DOI: 10.1371/journal.pone.0058870.

Enhanced Cellular Uptake of Peptide-Targeted Nanoparticles through Increased Peptide Hydrophilicity and Optimized Ethylene Glycol Peptide-Linker Length. Jared F. Stefanick, Jonathan D. Ashley, and Basar Bilgicer. ACS Nano. 2013, 7 (9) pp 8115–8127. August 29, 2013. DOI: 10.1021/nn4033954.

PulmoBind, an Adrenomedullin-Based Molecular Lung Imaging Tool. Myriam Létourneau, Quang Trinh Nguyen, Francois Harel, Alain Fournier, and Jocelyn Dupuis. J Nucl Med. 2013, 54 (10) pp 1789-1796. October 1, 2013. DOI:10.2967/jnumed.112.118984.

Liposomes containing monophosphoryl lipid A: A potent adjuvant system for inducing antibodies to heroin hapten analogs. Gary R. Matyas, Alexander V. Mayorova, Kenner C. Rice, Arthur E. Jacobson, Kejun Cheng, Malliga R. Iyer, Fuying Li, Zoltan Becka, Kim D. Janda, Carl R. Alvinga. Vaccine. 2013, 31 (26) pp 2804-2810. June 10, 2013. DOI:.org/10.1016/j.vaccine.2013.04.027.

Design of a heterotetravalent synthetic allergen that reflects epitope heterogeneity and IgE antibody variability to study mast cell degranulation. Michael W. Handlogten, Tanyel Kiziltepe and Basar Bilgicer. Biochem. J. 2013, 449 pp 91–99. October 11, 2011. DOI:10.1042/BJ20121088.

Design of a Heterobivalent Ligand to Inhibit IgE Clustering on Mast Cells. Michael W. Handlogten, Tanyel Kiziltepe, Demetri T. Moustakas, and Basxar Bilgicer. Chemistry & Biology. 2011, 18 (9) pp 1179–1188. September 23, 2011. DOI 10.1016/j.chembiol.2011.06.012.

Robust Sensing Films for Pathogen Detection and Medical Diagnostics. Aaron S. Anderson ; Andrew M. Dattelbaum ; Harshini Mukundan ;Dominique N. Price ; W. Kevin Grace ; Basil I. Swanson. Frontiers in Pathogen Detection: From Nanosensors to Systems., 2009, Proc. Of SPIE 7167. 71670q-1 February 18, 2009. 10.1117/12.809383.

Optical Imaging of Integrin αv β3 Expression with Near-Infrared Fluorescent RGD Dimer with Tetra(ethylene glycol) Linkers. Zhaofei Liu, Shuanglong Liu, Gang Niu, Fan Wang, Shuang Liu, Xiaoyuan Chen. Mol Imaging. 2010, 9 (1) pp 21-29. February 1, 2010. DOI: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629979/.

Spring-Loaded Model Revisited: Paramyxovirus Fusion Requires Engagement of a Receptor Binding Protein beyond Initial Triggering of the Fusion Protein. Matteo Porotto, Ilaria DeVito, Samantha G. Palmer, Eric M. Jurgens, Jia L. Yee, Christine C. Yokoyama, Antonello Pessi and Anne Moscona. J. Virol. 2011, 85 (24) pp 12867-12880. DOI: 10.1128/JVI.05873-11.

Tumor Uptake of the RGD Dimeric Probe 99mTc-G3-2P4-RGD2 is Correlated with Integrin rv_3 Expressed on both Tumor Cells and Neovasculature. Zhaofei Liu, Bing Jia, Jiyun Shi, Xiaona Jin, Huiyun Zhao, Fang Li, Shuang Liu, and Fan Wang. Bioconjugate Chem. 2010, 21 (3) pp 548-555. February 25, 2010. DOI: 10.1021/bc900547d.

Quantifying Cellular Internalization with a Fluorescent Click Sensor. Laura I. Selby, Luigi Aurelio, Daniel Yuen, Bim Graham, and Angus P. R. Johnston. ACS Sensors. 2018, 3, pp 1182-1189. April 20, 2018. DOI: 10.1021/acssensors.8b00219.

Radionuclides in Targeted Therapy of Cancer. Adina Elena STANCIU. Rev. Roum. Chim. 2012, 57 (1) pp 5-13. May 27, 2011. DOI: http://web.icf.ro/rrch/.

Improving Tumor-Targeting Capability and Pharmacokinetics of 99mTc-Labeled Cyclic RGD Dimers with PEG4 Linkers. Lijun Wang, Jiyun Shi, Young-Seung Kim, Shizhen Zhai, Bing Jia, Huiyun Zhao, Zhaofei Liu, Fan Wang, Xiaoyuan Chen and Shuang Liu. Molecular Pharmaceutics. 2009, 6 (1) pp 231–245. December 9, 2008. DOI: 10.1021/mp800150r.

Improving Tumor Uptake and Pharmacokinetics of 64Cu-Labeled Cyclic RGD Peptide Dimers with Gly3 and PEG4 Linkers. Jiyun Shi, Young-Seung Kim, Shizhen Zhai, Zhaofei Liu, Xiaoyuan Chen and Shuang Liu. Bioconjugate Chemistry. 2009, 20 (4) pp 750–759. March 25, 2009. DOI: 10.1021/bc800455p.

Evaluation of the Pharmacokinetic Effects of Various Linking Group Using the 111In-DOTA-X-BBN(7−14)NH2 Structural Paradigm in a Prostate Cancer Model. Jered C. Garrison, Tammy L. Rold, Gary L. Sieckman, Farah Naz, Samantha V. Sublett, Said Daibes Figueroa, Wynn A. Volkert and Timothy J. Hoffman. Bioconjugate Chem. 2008, 19 (9) pp 1803–1812. August 20, 2008. DOI: 10.1021/bc8001375.

Two 90Y-Labeled Multimeric RGD Peptides RGD4 and 3PRGD2 for Integrin Targeted Radionuclide Therapy. Zhaofei Liu, Jiyun Shi, Bing Jia, Zilin Yu, Yan Liu, Huiyun Zhao, Fang Li, Jie Tian, Xiaoyuan Chen, Shuang Liu, and Fan Wang.Two 90Y-Labeled Multimeric RGD Peptides RGD4 and 3PRGD2 for Integrin Targeted Radionuclide Therapy. Zhaofei Liu, Jiyun Shi, Bing Jia, Zilin Yu, Yan Liu, Huiyun Zhao, Fang Li, Jie Tian, Xiaoyuan Chen, Shuang Liu, and Fan Wang. Mol. Pharmaceutics. 2011, 8 (2) pp 591–599. January 19, 2011. DOI: 10.1021/mp100403y.

Impact of PKM Linkers on Biodistribution Characteristics of the 99mTc-Labeled Cyclic RGDfK Dimer. Shuang Liu, Zhengjie He, Wen-Yuan Hsieh, Young-Seung Kim, and Young Jiang. Bioconjugate Chem. 2006, 17 (6) pp 1499–1507. November 1, 2006. DOI: 10.1021/bc060235l.

99mTc-Galacto-RGD2: A Novel 99mTc-Labeled Cyclic RGD Peptide Dimer Useful for Tumor Imaging. Shundong Ji, Andrzej Czerwinski, Yang Zhou, Guoqiang Shao, Francisco Valenzuela, Paweł Sowiński, Satendra Chauhan, Michael Pennington, and Shuang Liu. Mol. Pharmaceutics. 2013, 10 (9) pp 3304–3314. July 22, 2013. DOI: 10.1021/mp400085d.

2-Mercaptoacetylglycylglycyl (MAG2) as a Bifunctional Chelator for 99mTc-Labeling of Cyclic RGD Dimers: Effect of Technetium Chelate on Tumor Uptake and Pharmacokinetics. Jiyun Shi, Young-Seung Kim, Sudipta Chakraborty, Bing Jia, Fan Wang and Shuang Liu. Bioconjugate Chemistry. 2009, 20(8) pp 1559–1568. July 15, 2009. DOI: 10.1021/bc9001739.

Robust Sensing Films for Pathogen Detection and Medical Diagnostics. Aaron S. Anderson ; Andrew M. Dattelbaum ; Harshini Mukundan ;Dominique N. Price ; W. Kevin Grace ; Basil I. Swanson. Frontiers in Pathogen Detection: From Nanosensors to Systems., 2009, Proc. Of SPIE 7167. 71670q-1 February 18, 2009. 10.1117/12.809383.

PEG-Peptide Conjugates. Ian W Hamley. Biomacromolecules. 2014. April 1, 2014. DOI: 10.1021/bm500246w.

Molecular Imaging of the Human Pulmonary Vascular Endothelium Using an Adrenomedullin Receptor Ligand. Francois Harel, Xavier Levac, Quang T. Nguyen, Myriam Le´tourneau, Sophie Marcil, Vincent Finnerty, Marie`ve Cossette, Alain Fournier, and Jocelyn Dupuis. Molecular Imaging. 2015, pp 1-9. March 1, 2015. DOI: 10.2310/7290.2015.00003.

Toward the Optimization of Bombesin-Based Radiotracers for Tumor Targeting. Ibai E. Valverde, Sandra Vomstein, and Thomas L. Mindt. Journal of Medicinal Chemistry. 2016, April 7, 2016. DOI: 10.1021/acs.jmedchem.6b00025.

In vitro and in vivo efficacy, toxicity, bio-distribution and resistance selection of a novel antibacterial drug candidate. Jlenia Brunetti, Chiara Falciani, Giulia Roscia, Simona Pollini, Stefano Bindi, Silvia Scali, Unai Cossio Arrieta, Vanessa Gomez-Vallejo, Leila Quercini, Elisa Lbba, Marco Prato, Gian Maria Rossolini, Jordi Llop, Luisa Bracci, and Alessandro Pini. Scientific Reports. 2016, 6 (26077). May 12, 2016. DOI: 10.1038/srep26077.

Multimodal Assessment of Mesenchymal Stem Cell Therapy for Diabetic Vascular Complications. Jamila Hedhli, Christian J. Konopka, Sarah Schuh, Hannah Bouvin, John A. Cole, Heather D. Huntsman, Kristopher A. Kilian, Iwona T. Dobrucki, Marni D. Boppart, and Lawrence W. Dobrucki. Theranostics. 2017, 7(16) pp 3876-3888. September 5, 2017. DOI: 10.7150/thno.19547.

Simplified lipid II-binding antimicrobial peptides: Design, synthesis and antimicrobial activity of bioconjugates of nisin rings A and B with pore-forming peptides. Serena A.Mitchell, FionaTruscott, RachaelDickman, JohnWard, Alethea B.Tabora. Bioorganic & Medicinal Chemistry. 2018, 26 (21) pp 5691-5700. October 19, 2018.

Designer covalent heterobivalent inhibitors prevent IgE-dependent responses to peanut allergen. Peter E. Deak, Baksun Kim, Amina Abdul Qayum, Jaeho Shin, Girish Vitalpur, Kirsten M. Kloepfer, Matthew J. Turner, Neal Smith, Wayne G. Shreffler, Tanyel Kiziltepe, Mark H. Kaplan, and Basar Bilgicer. 2019. April 8, 2019. DOI: 10.1073/pnas.1820417116
Fmoc-N-amido-dPEG®₅-acid (#10053)
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Design of a modular tetrameric scaffold for the synthesis of membrane-localized D-peptide inhibitors of HIV-1 entry. J. Nicholas Francis, Joseph S Redman, Debra M Eckert, and Michael S. Kay. Bioconjugate Chemistry. 2012, 23 (6), pp 1252-1258. May 1, 2012. DOI: 10.1021/bc300076f.

Enhanced Cellular Uptake of Peptide-Targeted Nanoparticles through Increased Peptide Hydrophilicity and Optimized Ethylene Glycol Peptide-Linker Length. Jared F. Stefanick, Jonathan D. Ashley, and Basar Bilgicer. ACS Nano. 2013, 7 (9) pp 8115–8127. August 29, 2013. DOI: 10.1021/nn4033954.

Folate-dactolisib conjugates for targeting tubular cells in polycystic kidneys. Haili Shi, Wouter N. Leonhard, Niels J. Sijbrandi, Mies J. van Steenbergen, Marcel H.A.M.Fens, Joep B.van de Dikkenberg, Javier SastreToraño, Dorien J.M.Peters, Wim E.Hennink, and Robbert Jan Kok. Journal of Controlled Release. 2019, 293 pp 113-125. November 23, 2018. https://doi.org/10.1016/j.jconrel.2018.11.019.
Fmoc-N-amido-dPEG®₆-acid (#10063)
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Polyproline-Rod Approach to Isolating Protein Targets of Bioactive Small Molecules: Isolation of a New Target of Indomethacin. Shin-ichi Sato, Youngjoo Kwon, Shinji Kamisuki, Neeta Srivastava, Quian Mao, Yoshinori Kawazoe, and Motonari Uesugi. J. Am. Chem. Soc. 2007, 129 (4), pp 873–880. January 4, 2007. DOI: 10.1021/ja0655643.

Design and Synthesis of Multifunctional Gold Nanoparticles Bearing Tumor-Associated Glycopeptide Antigens as Potential Cancer Vaccines. Raymond P. Brinãs, Andreas Sundgren, Padmini Sahoo, Susan Morey, Kate Rittenhouse-Olson, Greg E. Wilding, Wei Deng, and Joseph J. Barchi, Jr. Bioconjugate Chem. 2012, 23 (8), pp 1513-1523. July 19, 2012. DOI: 10.1021/bc200606s.

Mechanistic Studies of a Peptidic GRP78 Ligand for Cancer Cell-Specific Drug Delivery. Ying Liu, Sebastian C.J. Steiniger, YoungSoo Kim, Gunnar F. Kaufmann, Brunhilde Felding-Habermann, and Kim D. Janda. Molecular Pharmaceutics 2007 4(3) p 435-447. January 2007. DOI:10.1021/mp060122j.

Multifunctional nanoparticles as simulants for a gravimetric Immunoassay. Scott A. Miller, Leslie A. Hiatt, Robert G. Keil, David W. Wright, and David E. Cliffel. Analytical and Bioanalytical Chemistry. 2011, 399 (3) pp 1021-1029 January 1, 2011. DOI:10.1007/s00216-010-4419-8.

Evaluation of Phage Display Discovered Peptides as Ligands for Prostate-Specific Membrane Antigen (PSMA). Duanwen Shen, Fei Xie, W. Barry Edwards. PLoS ONE. 2013, 8 (7), pp e68339. July 25, 2013. DOI: 10.1371/journal.pone.0068339.

A Systematic Analysis of Peptide Linker Length and Liposomal Polyethylene Glycol Coating on Cellular Uptake of Peptide-Targeted Liposomes. Jared F. Stefanick, Jonathan D. Ashley, Tanyel Kiziltepe, and Basar Bilgicer. ACS Nano. 2013, 7 (4) pp 2935–2947. February 19, 2013. DOI: 10.1021/nn305663e.

Enhanced Cellular Uptake of Peptide-Targeted Nanoparticles through Increased Peptide Hydrophilicity and Optimized Ethylene Glycol Peptide-Linker Length. Jared F. Stefanick, Jonathan D. Ashley, and Basar Bilgicer. ACS Nano. 2013, 7 (9) pp 8115–8127. August 29, 2013. DOI: 10.1021/nn4033954.

Novel Monodisperse PEGtide Dendrons: Design, Fabrication, and Evaluation of Mannose Receptor-Mediated Macrophage Targeting. Jieming Gao, Peiming Chen, Yashveer Singh, Xiaoping Zhang, Zoltan Szekely, Stanley Stein, and Patrick J. Sinko. Bioconjugate Chem. 2013, 24 (8) pp 1332–1344. June 29, 2013. DOI: 10.1021/bc400011v.

B-Peptide Conjugates: Syntheses and CD and NMR Investigations of B/a-Chimeric Peptides, of a DPA-B-Decapeptide, and of a PEGylated b-Heptapeptide. James Gardiner, Raveendra I. Mathad, Berhard Jaun, Jurg V. Schreiber, Oliver Flogel, and Dieter Seebach. Helvetica Chimica Acta. 2009, 92 (12) pp 2698-2721. December 17, 2009. DOI: 10.1002/hlca.200900325.

Immunomodulation of the NLRP3 Inflammasome through Structure-Based Activator Design and Functional Regulation via Lysosomal Rupture. Saikat Manna, William J. Howitz, Nathan J. Oldenhuis, Alexander C. Eldredge, Jingjing Shen, Fnu Naorem Nihesh, Melissa B. Lodoen, Zhibin Guan, and Aaron P. Esser-Kahn. ACS Central Science. 2018, 4, pp 982-995. July 2, 2018. DOI: 10.1021/acscentsci.8b00218.

PEG-Peptide Conjugates. Ian W Hamley. Biomacromolecules. 2014. April 1, 2014. DOI: 10.1021/bm500246w.

Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy. Magdalena Dorywalska, Pavel Strop, Jody A. Melton-Witt, Adela Hasa-Moreno, Santiago E. Farias, Meritxell Galindo Casas, Kathy Delaria, Victor Lui, Kris Poulsen, Janette Sutton, Gary Bolton, Dahui Zhou, Ludivine Moine, Russell Dushin, Thomas-Jaume Pons, Arvind Rajpal. Plos One. 2015, 10 (7) e0132282. July 10, 2015. DOI: 10.1371/journal.pone.0132282.

A Synthetic Virus-Like Particle Streptococcal Vaccine Candidate Using B-Cell Epitopes from the Proline-Rich Region of Pneumococcal Surface Protein A. Marco Tamborrini, Nina Geib, Aniebrys Marrero-Nodarse, Maja Jud, Julia Hauser, Celestine Aho, Araceli Lamelas, Armando Zuniga, Gerd Pluschke, Arin Ghasparian and John A. Robinson. Vaccines. 2015, 3 (4), pp 850-874, October 16, 2015. DOI: 10.3390/vaccines3040850.

Nanoallergens: A multivalent platform for studying and evaluating potency of allergen epitopes in cellular degranulation. Peter E Deak, Maura R Vrabel, Vincenzo J Pizzuti, Tanyel Kiziltepe, and Basar Bilgicer. Experimental Biology and Medicine. 2016, 0 pp 1-11. April 13, 2016. DOI: 10.1177/1535370216644533.

Control of strand registry by attachment of PEG chains to amyloid peptides influences nanostructure. Valeria Castelletto, Ge Cheng, Steve Furzeland, Derek Atkinsb and Ian W. Hamley. Soft matter. 2012, 8, pp 5434-5438. April 16, 2012. DOI:10.1039/C2SM25546D.
Fmoc-N-amido-dPEG®₈-acid (#10273)
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Polyproline-Rod Approach to Isolating Protein Targets of Bioactive Small Molecules: Isolation of a New Target of Indomethacin. Shin-ichi Sato, Youngjoo Kwon, Shinji Kamisuki, Neeta Srivastava, Quian Mao, Yoshinori Kawazoe, and Motonari Uesugi. Journal of the American Chemical Society. 2007, 129 (4), pp 873–880. January 4, 2007. DOI: 10.1021/ja0655643.

New Enzyme-Activated Solubility-Switchable Contrast Agent for Magnetic Resonance Imaging: From Synthesis to in Vivo Imaging. Beata Jastrzabska, Rejean Lebel, Helene Therriault, J. Oliver McIntyre, Emanuel Escher, Briggitte Guerin, Benoit Paquette, Witold A. Neugebauer, and Martin Lepage. Journal of Medicinal Chemistry. 2009, 52 (6) pp 1576–1581. February 19, 2009. DOI: 10.1021/jm801411h.

A Non-Chromatographic Method for the Purification of a Bivalently Active Monoclonal IgG Antibody from Biological Fluids. Basar Bilgicer, Samuel W. Thomas III, Bryan F. Shaw, George K. Kaufman, Vijay M. Krishnamurthy, Lara A. Estroff, Jerry Yang, and George M. Whitesides. Journal of the American Chemical Society. 2009, 131 (26) pp 9361–9367. June 17, 2009. DOI: 10.1021/ja9023836.

Photocleavable peptide-oligonucleotide conjugates for protein kinase assays by MALDI-TOF MS. Guangchang Zhou, Faraz Khan, Qing Dai, Juliesta E Sylvester and Stephen J Kron. Molecular BioSystems. 2012, 8 (9), pp 2395-2404. June 13, 2012. DOI: 10.1039/C2MB25163A.

A Synthetic Trivalent Hapten that Aggregates anti-2,4-DNP IgG into Bicyclic Trimers. Başar Bilgiçer, Demetri T. Moustakas, and George M. Whitesides. Journal of the American Chemical Society. 2007, 129 (12) pp 3722-3728. February 28, 2007. DOI: 10.1021/ja067159h.

Determination of bacterial viability by selective capture using surface-bound siderophores. Mark L. Wolfenden, Rama M. Sakamuri, Aaron S. Anderson, Lakshman Prasad, Jurgen G. Schmidt, Harshini Mukundan. Advances in Biological Chemistry. 2012, 2 (4) pp 396-402 September 30, 2012. DOI: 10.4236/abc.2012.24049.

Synthetic Allergen Design Reveals the Significance of Moderate Affinity Epitopes in Mast Cell Degranulation. Michael W. Handlogten, Tanyel Kiziltepe, Nathan J. Alves, and Basar Bilgicer. ACS Chemical Biology. 2012, 7 (11) pp 1796–1801. August 10, 2012. DOI: 10.1021/cb300193f.

Enhanced Cellular Uptake of Peptide-Targeted Nanoparticles through Increased Peptide Hydrophilicity and Optimized Ethylene Glycol Peptide-Linker Length. Jared F. Stefanick, Jonathan D. Ashley, and Basar Bilgicer. ACS Nano. 2013, 7 (9) pp 8115–8127. August 29, 2013. DOI: 10.1021/nn4033954.

Novel solubility-switchable MRI agent allows the noninvasive detection of matrix metalloproteinase-2 activity In vivo in a mouse model. Rejean Lebel, Beata Jastrzebska, Helene Therriault, Marie-Michele Cournoyer, J. Oliver McIntyre, Emanuel Escher, Witold Neugebauer, Benoit Paquette, and Martin Lepage. Magnetic Resonance in Medicine. 2008, 60 (5) pp 1056–1065. October 27, 2008. DOI: 10.1002/mrm.21741.

Design of a Heterotetravalent Synthetic Allergen That Reflects Epitope Heterogeneity and IgE Antibody Variability to Study Mast Cell Degranulation. Michael W. Handlogten, Tanyel Kiziltepe and Basar Bilgicer. Biochem. J. 2013, 449 (1) pp 91–99. January 1, 2013. DOI: 10.1042/BJ20121088.

Design of a Heterobivalent Ligand to Inhibit IgE Clustering on Mast Cells. Michael W. Handlogten, Tanyel Kiziltepe, Demetri T. Moustakas, and Basxar Bilgicer. Chemistry & Biology. 2011, 18 (9) pp 1179–1188. September 23, 2011. DOI: 10.1016/j.chembiol.2011.06.012.

Design of a Heterobivalent Inhibitor of Allergy and More Physiologically Relevant Allergy Models. Michael William Handlogten. University of Notre Dame. 2013, March 28, 2013.

PEG-Peptide Conjugates. Ian W Hamley. Biomacromolecules. 2014, 15 (5) pp 1543-1559. April 1, 2014. DOI: 10.1021/bm500246w.

Positron Emission Tomographic Imaging of Copper 64– and Gallium 68–Labeled Chelator Conjugates of

the Somatostatin Agonist Tyr3-Octreotate. Jessie R. Nedrow, Alexander G. White, Jalpa Modi, Kim Nguyen, Albert J. Chang and Carolyn J. Anderson. Molecular Imaging. 2014, 13 pp 1-13. Decebmer 14, 2014. DOI: 10.2310/7290.2014.00020.

Peripheral administration of a long-acting peptide OT receptor agonist inhibits fear induced freezing. Meera E. Modi, Mark J. Majchrzak, Kari R. Fonseca, Angela Doran, Sarah Osgood, Michelle Vanase-Frawley, Eric Feyfant, Heather McInnes, Ramin Darvari, Derek L. Buhl, and Natasha M. Kablaoui. JPET. 2016, 357 (3). May 23, 2016. DOI: 10.1124/jpet.116.232702.

Designer covalent heterobivalent inhibitors prevent IgE-dependent responses to peanut allergen. Peter E. Deak, Baksun Kim, Amina Abdul Qayum, Jaeho Shin, Girish Vitalpur, Kirsten M. Kloepfer, Matthew J. Turner, Neal Smith, Wayne G. Shreffler, Tanyel Kiziltepe, Mark H. Kaplan, and Basar Bilgicer. 2019. April 8, 2019. DOI: 10.1073/pnas.1820417116

Membrane-Fusogen Distance Is Critical for Efficient Coiled-Coil-Peptide-Mediated Liposome Fusion. Geert A. Daudey, Harshal R. Zope, Jens Voskuhl, Alexander Kros , and Aimee L. Boyle. Langmuir. 2017, 33 (43) pp 12443-12452. 10/5/2017. DOI: 10.1021/acs.langmuir.7b02931.
Fmoc-N-amido-dPEG®₁₂-acid (#10283)
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Optimization of Xenon Biosensors for Detection of Protein Interactions. Thomas J. Lowery, Sandra Garcia, Lana Chavez, E. Janette Ruiz, Tom Wu, Thierry Brotin, Jean-Pierre Dutasta, David S. King, Peter G. Schultz, Alex Pines, and David E. Wemmer. ChemBioChem. 2006, 7 (1), pp 65-73. January 9, 2006. DOI: 10.1002/cbic.200500327.

Monodispersed DOTA-PEG-Conjugated Anti-TAG-72 Diabody Has Low Kidney Uptake and High Tumor-to-Blood Ratios FResulting in Improved Cu PET. Lin Li, Fabio Turatti, Desiree Crow, James R. Bading, Anne-Line Anderson, Erasmus Poku, Paul J. Yazaki, Lawrence E. Williams, Debra Tamvakis, Paul Sanders, David Leong, Andrew Raubitschek, peter J. Hudson, David Colcher, and John E. Shively. Journal of Nuclear Medicine. 2010, 51 (7), pp 1139-1146. June 16, 2010. DOI: 10.2967/jnumed.109.074153.

Photocleavable Peptide-Conjugated Magnetic Beads for Protein Kinase Assays by MALDI-TOF. MS. Guangchang Zhou, Xiaoliang Yan, Ding Wu, and Stephen J. Kron. Bioconjugate Chemistry. 2010, 21 (10), pp 1917–1924. September 22, 2010. DOI: 10.1021/bc1003058.

Neutrophil Targeting Heterobivalent SPECT Imaging Probe: cFLFLF-PEG-TKPPR-99mTc. Yi Zhang, Li Xiao, Mahendra D. Chordia, Landon W. Locke, Mark B. Williams, Stuart S. Berr, and Dongfeng Pan. Bioconjugate Chemistry. 2010, 21 (10), pp 1788–1793 September 15, 2010. DOI: 10.1021/bc100063a.

Calcium Condensed LABL-TAT Complexes Effectively Target Gene Delivery to ICAM-1 Expressing Cells. Supang Khondee, Abdulgader Baoum, Teruna J. Siahaan, and Cory Berkland. Molecular Pharmaceutics. 2011, 8 (3), pp 788–798. April 7, 2011. DOI: 10.1021/mp100393j.

Site-Specific Conjugation of Monodispersed DOTA-PEGn to a Thiolated Diabody Reveals the Effect of Increasing PEG Size on Kidney Clearance and Tumor Uptake with Improved 64-Copper PET Imaging. Lin Li,Desiree Crow, Fabio Turatti, James R. Bading, Anne-Line Anderson, Erasmus Poku, Paul J. Yazaki, Jenny Carmichael, David Leong, Michael P. Wheatcroft,Andrew A. Raubitschek, Peter J. Hudson,David Colcher, and John E. Shively. Bioconjugate Chemistry. 2011, 22 (4), pp 709–716. March 12, 2011. DOI: 10.1021/bc100464e.

Flexible antibodies with nonprotein hinges. Daniel J. Capon, Naoki Kaneko, Takayuki Yoshimori, Takashi Shimada, Florian M. Wurm, Peter K. Hwang, Xiaohe Tong, Staci A. Adams, Graham Simmons, Taka-Aki Sato and Koichi Tanaka. The Japan Academy Series B Physical and Biological Sciences. 2011, 87 (9), pp 603-616. November 11, 2011. DOI: 10.2183/pjab.87.603.

Enhanced Cellular Uptake of Peptide-Targeted Nanoparticles through Increased Peptide Hydrophilicity and Optimized Ethylene Glycol Peptide-Linker Length. Jared F. Stefanick, Jonathan D. Ashley, and Basar Bilgicer. ACS Nano. 2013, 7 (9) pp 8115-8127. August 29, 2013. DOI: 10.1021/nn4033954.

A Systematic Analysis of Peptide Linker Length and Liposomal Polyethylene Glycol Coating on Cellular Uptake of Peptide-Targeted Liposomes. Jared F. Stefanick, Jonathan D. Ashley, Tanyel Kiziltepe, and Basar Bilgicer. ACS Nano. 2013, 7 (4) pp 2935–2947. February 19, 2013. DOI: 10.1021/nn305663e.

Enhanced Cellular Uptake of Peptide-Targeted Nanoparticles through Increased Peptide Hydrophilicity and Optimized Ethylene Glycol Peptide-Linker Length. Jared F. Stefanick, Jonathan D. Ashley, and Basar Bilgicer. ACS Nano. 2013, 7 (9) pp 8115–8127. August 29, 2013. DOI: 10.1021/nn4033954.

Oriented Surface Immobilization of Antibodies at the Conserved Nucleotide Binding Site for Enhanced Antigen Detection. Nathan J Alves, Tanyel Kiziltepe, and Basar Bilgicer. Langmuir. 2012, 28 (25) pp 9640–9648. May 21, 2012. DOI: 10.1021/la301887s.

Hepatocyte Targeting of Nucleic Acid Complexes and Liposomes by a T7 Phage p17 Peptide. So C. Wong, Darren Wakefield, Jason Klein, Sean D. Monahan, David B. Rozema, David L. Lewis, Lori Higgs, James Ludtke, Alex V. Sokoloff, and Jon A. Wolff. Molecular Pharmaceutics. 2006, 3 (4) pp 386-397. March 28, 2006. DOI: 10.1021/mp050108r.

Evaluation of Nonpeptidic Ligand Conjugates for SPECT Imaging of Hypoxic and Carbonic Anhydrase IX-Expressing Cancers. Peng-Cheng Lv, Karson S. Putt, and Philip S. Low. Bioconjugate Chemistry. 2016, 27, pp 1762-1769. June 30, 2016. DOI: 10.1021/acs.bioconjchem.6b00271.

Synthesis of the Cyanine 7 labeled neutrophil-specific agents for noninvasive near infrared fluorescence imaging. Xiao L, Zhang Y, Liu Z, Yang M, Pu L, Pan D. Bioorganic & Medicinal Chemistry Letters. 2010, 20 (12) pp 3515-3517. June 15, 2010. DOI: 10.1016/j.bmcl.2010.04.136.

PEG-Peptide Conjugates. Ian W Hamley. Biomacromolecules. 2014, 15 (5) pp 1543-1559. April 1, 2014. DOI: 10.1021/bm500246w.

Controlled liposome fusion mediated by SNARE protein mimics. Hana Robson Marsden, Alexander V. Korobko,Tingting Zheng, Jens Voskuhla and Alexander Kros. Biomaterials Science. 2013, 1 (10) pp 1046-1054. June 4, 2013. DOI: 10.1039/C3BM60040H.

SNARE protein analog-mediated membrane fusion. Pawan Kumar, Samit Guha and Ulf Diederichsen. Journal of Peptide Science. 2015, April 7, 2015. DOI: 10.1002/psc.2773.

In Situ Modification of Plain Liposomes with Lipidated Coiled Coil Forming Peptides Induces Membrane Fusion. Frank Versluis , Jens Voskuhl , Bartjan van Kolck , Harshal Zope , Marien Bremmer , Tjerk Albregtse and Alexander Kros. Journal of the American Chemical Society. 2013, 135 (21), pp 8057–8062. May 9, 2013. DOI: 10.1021/ja4031227.

A Reduced SNARE Model for Membrane Fusion. Hana Robson Marsden, Nina A. Elbers, Paul H., H. Bomans, Nico A.J.M.Sommerdijk and Alexander Kros. Communications. 2009, 48 pp 2330-2333. February 16, 2009. DOI: 10.1002/anie.200804493.

Insights into the role of sulfated glycans in cancer cell adhesion and migration through use of branched peptide probe. Jlenia Brunetti, Lorenzo Depau, Chiara Falciani, Mariangela Gentile, Elisabetta Mandarini, Giulia Riolo, Pietro Lupetti, Alessandro Pini, and Luisa Bracci. Scientific Reports. 2016, 6 (27174). June 3, 2016. DOI: 10.1038/srep27174.

Bioresponsive nanocarries for targeted intracellular delivery of proteins and peptides. Ruth Elisabeth and Johanna Roder. Dissertation zur Erlangung des Doktorgrades der Fakultat fur Chemie und Pharmazie der Ludwig-Maximilians-Universitat Munchen. 2016, pp 1-128.

Bioresponsive nanocarries for targeted intracellular delivery of proteins and peptides. Ruth Elisabeth and Johanna Roder. Dissertation zur Erlangung des Doktorgrades der Fakultat fur Chemie und Pharmazie der Ludwig-Maximilians-Universitat Munchen. 2016, pp 1-128.

Influence of Defined Hydrophilic Blocks within Oligoaminoamide Copolymers: Compaction versus Sheilding of pDNA Nanoparticles. Stephan Morys, Ana Krhac Levacic, Sarah Urnauer, Susanne Kempter, Sarah Kern, Joachim O Radler, Christine Spitzweg, Ulrich Lachelt, and Ernst Wagner. Polymers. 2017, 9 (4) pp 1-20. April 19, 2017. DOI: 10.3390/polym9040142.

Control of strand registry by attachment of PEG chains to amyloid peptides influences nanostructure. Valeria Castelletto, Ge Cheng, Steve Furzeland, Derek Atkinsb and Ian W. Hamley. Soft matter. 2012, 8, pp 5434-5438. April 16, 2012. DOI:10.1039/C2SM25546D.

Morphological Transformation of Peptide Nanoassemblies through Conformational Transition of Core-forming Peptides. Tomonori Waku, Naoyuki Hirata, Masamichi Nozaki, Kanta Nogami, Shigeru Kunugi and Naoki Tanaka. Polymers. 2018, 11 (1), 39. December 28, 2018. https://doi.org/10.3390/polym11010039

Membrane-Fusogen Distance Is Critical for Efficient Coiled-Coil-Peptide-Mediated Liposome Fusion. Geert A. Daudey, Harshal R. Zope, Jens Voskuhl, Alexander Kros , and Aimee L. Boyle. Langmuir. 2017, 33 (43) pp 12443-12452. 10/5/2017. DOI: 10.1021/acs.langmuir.7b02931.

Use of a leukocyte-targeted peptide probe as a potential tracer for imaging the tuberculosis granuloma. Landon W. Locke, Shankaran Kothandaraman, Michael Tweedle, Sarah Chaney, Daniel J. Wozniak, and Larry S. Schlesinger. Tuberculosis. 2018, 108 pp 201-210. January 8, 2018. DOI: 10.1016/j.tube.2018.01.001.

Coiled-coil formation of the membrane-fusion K/E peptides viewed by electron paramagnetic resonance. Pravin Kumar, Martin van Son, Tingting Zheng, Dayenne Valdink, Jan Raap, Alexander Kros, and Martina Huber. PLOS ONE. 2018, 13 (1) pp 1-13. January 19, 2018. DOI: 10.1371/journal.pone.0191197.

Near-infrared quantum dots labelled with a tumor selective tetrabranched peptide for in vivo imaging. Jlenia Brunetti, Giulia Riolo, Mariangela Gentile, Andrea Bernini, Eugenio Paccagnini, Chiara Falciani, Luisa Lozzi, Silvia Scali, Lorenzo Depau, Alessandro Pini, Pietro Lupetti, and Luisa Bracci. Journal of Nanobiotechnology. 2018, 16 (21) pp. 1-10. March 3, 2018. DOI: 10.1186/s12951-018-0346-1.
Fmoc-N-amido-dPEG®₂₄-acid (#10313)
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Effect of PEGylation of N-WASP181-200 on the Inhibitory Potency for Renal Aminoglycoside Accumulation. Kenju Fujii, Junya Nagai, Takeshi Sawada, Ryko Yumoto, and Mikihisa Takano, Bioconjugate Chemistry. 2009, 20 (8), pp 1553–1558 July 2, 2009. DOI: 10.1021/bc900094g.

Site-Specific Conjugation of Monodispersed DOTA-PEGn to a Thiolated Diabody Reveals the Effect of Increasing PEG Size on Kidney Clearance and Tumor Uptake with Improved 64-Copper PET Imaging. Lin Li,Desiree Crow, Fabio Turatti, James R. Bading, Anne-Line Anderson, Erasmus Poku, Paul J. Yazaki, Jenny Carmichael, David Leong, Michael P. Wheatcroft,Andrew A. Raubitschek, Peter J. Hudson,David Colcher, and John E. Shively.Bioconjugate Chemistry. 2011, 22 (4), pp 709–716 March 12, 2011. DOI: 10.1021/bc100464e.

Flexible antibodies with nonprotein hinges. Daniel J. Capon, Naoki Kaneko, Takayuki Yoshimori, Takashi Shimada, Florian M. Wurm, Peter K. Hwang, Xiaohe Tong, Staci A. Adams, Graham Simmons, Taka-Aki Sato and Koichi Tanaka. The Japan Academy. 2011, 87 (9) pp 603-616. November 11, 2011. DOI: 10.2183/pjab.87.603.

Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing. Christian Dohmen, Thomas Fröhlich, Ulrich Lächelt, Ingo Röhl, Hans-Peter Vornlocher, Philipp Hadwiger and Ernst Wagner. Molecular Therapy Nucleic Acids. 2012, 1 (e7) January 31, 2012. DOI: 10.1038/mtna.2011.10.

Precise and multifunctional conjugates for targeted siRNA delivery. Prof. Dr. Ernst Wagner Prof. Dr. Wolfgang Friess. Dissertation zur Erlangung des Doktorgrades der Fakultät für Chemie und Pharmazie der Ludwig-Maximilians-Universität München. April 27, 2012.

Enhanced Cellular Uptake of Peptide-Targeted Nanoparticles through Increased Peptide Hydrophilicity and Optimized Ethylene Glycol Peptide-Linker Length. Jared F. Stefanick, Jonathan D. Ashley, and Basar Bilgicer. ACS Nano. 2013, 7 (9) pp 8115-8127. August 29, 2013. DOI: 10.1021/nn4033954.

A Systematic Analysis of Peptide Linker Length and Liposomal Polyethylene Glycol Coating on Cellular Uptake of Peptide-Targeted Liposomes. Jared F. Stefanick, Jonathan D. Ashley, Tanyel Kiziltepe, and Basar Bilgicer. ACS Nano. 2013, 7 (4) pp 2935–2947. February 19, 2013. DOI: 10.1021/nn305663e.

Enhanced Cellular Uptake of Peptide-Targeted Nanoparticles through Increased Peptide Hydrophilicity and Optimized Ethylene Glycol Peptide-Linker Length. Jared F. Stefanick, Jonathan D. Ashley, and Basar Bilgicer. ACS Nano. 2013, 7 (9) pp 8115–8127. August 29, 2013. DOI: 10.1021/nn4033954.

Solid-phase-assisted synthesis of targeting peptide–PEG–oligo(ethane amino) amides for receptor-mediated gene delivery. Irene Martin, Christian Dohmen, Carlos Mas-Moruno, Christina Troiber, Petra Kos, David Schaffert, Ulrich Lächelt, Meritxell Teixidó, Michael Günther, Horst Kessler, Ernest Giralt and Ernst Wagner. Organic & Biomolecular Chemistry. 2012, 10 pp 3258-3268. February 23, 2012. DOI: 10.1039/C2OB06907E.

Design of a Heterobivalent Ligand to Inhibit IgE Clustering on Mast Cells. Michael W. Handlogten, Tanyel Kiziltepe, Demetri T. Moustakas, and Basxar Bilgicer. Chemistry & Biology. 2011, 18 (9) pp 1179–1188. September 23, 2011. DOI: 10.1016/j.chembiol.2011.06.012.

Design of a Heterobivalent Inhibitor of Allergy and More Physiologically Relevant Allergy Models. Michael William Handlogten. University of Notre Dame. 2013, March 28, 2013.

PEG-Peptide Conjugates. Ian W Hamley. Biomacromolecules. 2014, 15 (5) pp 1543-1559. April 1, 2014. DOI: 10.1021/bm500246w.

Synthetic Polyglutamylation of Dual-Functional MTX Ligands for Enhanced Combined Cytotoxicity of Poly(I:C) Nanoplexes. Ulrich Lächelt Valentin Wittmann, Katharina Müller, Daniel Edinger, Petra Kos, Miriam Höhn, and Ernst Wagner. Molecular Pharmaceutics. 2014, 11 (8) pp 2631-2639. April 22, 2014. DOI: 10.1021/MP500017u.

Histidine-rich stabilized polyplexes for cMet-directed tumor-targeted gene transfer. Petra Kos, Ulrich Lachelt, Annika Herrmann, Fruke Martina Mickler, Markus Doblinger, Dongsheng He, Ana Krhac Levacic, Stephan Morys, Christoph Brauchle, and Ernst Wagner. Nanoscale. 2015, 7 (12), pp 5350-5362 February 15, 2015. DOI: 10.1039/c4nr06556e.

Nanosized Multifunctional Polyplexes for Receptor-Mediated SiRNA Delivery. Christian Dohmen, Daniel Edinger, Thomas Frohlich, Laura Schreiner, Ulrich Lachelt, Christina Troiber, Joachim Radler, Philipp Hadwiger, Hans-Peter Vornlocher, and Ernst Wagner. ACS Nano. 2012, 6 (6), pp 5198-5208. May 30, 2012. DOI: 10.1021/nn300960m.

Combinatorial optimization of sequence-defined oligo(ethanamino)amides for folate receptor-targeted pDNA and siRNA delivery. Dongsheng He, Katharina Muller, Ana Krhac, Petra Kos, Ulrich Lachelt, and Ernst Wagner. Bioconjugate Chemistry. 2016, January 3, 2016. DOI: 10.1021/acs.bioconjchem.5b00649.

Combinal optimization of nucleic acid carriers for folate-targeted delivery. Dongsheng He. 2016.

Orthogonal Cysteine Protection Enables Homogeneous Multi-Drug Antibody-Drug Conjugates. Matthew R Levengood, Xinqun Zhang, Joshua H Hunter, Kim K Emmerton, Jamie B Miyamoto, Timothy S Lewis, and Peter D Senter. Angewandte Chemie. 2016, 55 pp 1-6. December 14, 2016. DOI: 10.1002/anie.201608292.

Oligaminoamide-Based siRNA Formulations for Folate Receptor-Directed Tumor Targeting and Gene Silencing. Dian-Jang Lee. The Faculty of Chemistry and Pharmacy. 2016, pp 1-107. March 11, 2016.

Influence of Defined Hydrophilic Blocks within Oligoaminoamide Copolymers: Compaction versus Sheilding of pDNA Nanoparticles. Stephan Morys, Ana Krhac Levacic, Sarah Urnauer, Susanne Kempter, Sarah Kern, Joachim O Radler, Christine Spitzweg, Ulrich Lachelt, and Ernst Wagner. Polymers. 2017, 9 (4) pp 1-20. April 19, 2017. DOI: 10.3390/polym9040142.

Systemic Delivery of Folate-PEG siRNA Lipopolyplexes with Enhanced Intracellular Intracellular Stability for In Vivo Gene Silencing in Leukemia. Dian-Jang Lee, Eva Kessel, Taavi Lehto, Xueying Liu, Naoto Yoshinaga, Kart Padari, Ying-Chen Chen, Susanne Kempter, Satoshi Uchida, Joachim O. Radler, Margus Pooga, Ming-Thau Sheu, Kazunori Kataoka, and Ernst Wagner. Bioconjugate Chemistry. 2017, August 3, 2017. DOI: 10.1021/acs.bioconjchem.7b00383.

Protein Transduction by Lipo-Oligoaminoamide Nanoformulations. Peng Zhang. Dissertation zur Erlangung des Doktorgrades der Fakultat fur Chemie and Pharmazie der Ludwig-Maximilians-Universitat Munchen. 2017, pp 1-102. July 25, 2017. https://edoc.ub.uni-muenchen.de/21022/1/Zhang_Peng.pdf

Peptide Inhibitor of Complement C1 Inhibits the Peroxidase Activity of Hemoglobin and Myoglobin. Pamela S. Hair, Kenji M. Cunnion, and Neel K. Krishna. Hindawi International Journal of Peptides. 2017, 2017(9454583) pp 1-10. September 10, 2017. http://doi.org/10.1155/2017/9454583.

IL4‐Receptor‐Targeted Dual Antitumoral Apoptotic Peptide—siRNA Conjugate Lipoplexes. Jie Luo, Miriam Höhn, Soren Reinhard, Dominik M. Loy, Philipp Michael Klein, Ernst Wagner. Advanced Functional Materials. 2019. April 17, 2019. DOI: 10.1002/adfm.201900697

Tumoral gene silencing by receptor-targeted combinatorial siRNA polyplexes. Dian-Jang Lee, Dongsheng He, Eva Kessel, Kärt Padari, Susanne Kempter, Ulrich Lächelt, Joachim O. Rädler, Margus Pooga, Ernst Wagner. Journal of Controlled Release. 2016, 244 (B) pp 280-291. 12/28/2016. DOI: 10.1016/j.jconrel.2016.06.011.

Dual-Targeted Polyplexes Based on Sequence-Defined Peptide–PEG–Oligoamino Amides. Petra Kos,

Ulrich Lächelt, Dongsheng He, Yu Nie, Zhongwei Gu, and Ernst Wa. Journal of Pharmaceutical Sciences. 2014, 104 (2) pp 464-475. 9/29/2014. DOI: 10.1002/jps.24194.
Fmoc-N-amido-dPEG®₃₆-acid (#10903)
Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

Lipo-Oligomer Nanoformulations for Targeted Intracellular Protein Delivery. Peng Zhang, Benjamin Steinborn, Ulrich Lachelt, Stefan Zahler, and Ernst Wagner. Biomacromolecules. 2017, June 26, 2017. DOI: 10.1021/acs.biomac.7b00666.

Flexible antibodies with nonprotein hinges. Daniel J. Capon, Naoki Kaneko, Takayuki Yoshimori, Takashi Shimada, Florian M. Wurm, Peter K. Hwang, Xiaohe Tong, Staci A. Adams, Graham Simmons, Taka-Aki Sato and Koichi Tanaka. The Japan Academy, Series B. 2011, 87 (9) pp 603-616. November 11, 2011. DOI: 10.2183/pjab.87.603.

A Systematic Analysis of Peptide Linker Length and Liposomal Polyethylene Glycol Coating on Cellular Uptake of Peptide-Targeted Liposomes. Jared F. Stefanick, Jonathan D. Ashley, Tanyel Kiziltepe, and Basar Bilgicer. ACS Nano. 2013, 7 (4) pp 2935–2947. February 19, 2013. DOI: 10.1021/nn305663e.

Enhanced Cellular Uptake of Peptide-Targeted Nanoparticles through Increased Peptide Hydrophilicity and Optimized Ethylene Glycol Peptide-Linker Length. Jared F. Stefanick, Jonathan D. Ashley, and Basar Bilgicer. ACS Nano. 2013, 7 (9) pp 8115–8127. August 29, 2013. DOI: 10.1021/nn4033954.

PEG-Peptide Conjugates. Ian W Hamley. Biomacromolecules. 2014, 15 (5) pp 1543-1559. April 1, 2014. DOI: 10.1021/bm500246w.

Evaluation of Nonpeptidic Ligand Conjugates for SPECT Imaging of Hypoxic and Carbonic Anhydrase IX-Expressing Cancers. Peng-Cheng Lv, Karson S. Putt, and Philip S. Low. Bioconjugate Chemistry. 2016, 27, pp 1762-1769. June 30, 2016. DOI: 10.1021/acs.bioconjchem.6b00271.

Bioresponsive nanocarries for targeted intracellular delivery of proteins and peptides. Ruth Elisabeth and Johanna Roder. Dissertation zur Erlangung des Doktorgrades der Fakultat fur Chemie und Pharmazie der Ludwig-Maximilians-Universitat Munchen. 2016, pp 1-128.